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4E-BP1/EIF4EBP1

4E-BP1/EIF4EBP1 단백질 및 항체

Entrez Gene Summary for 4E-BP1/EIF4EBP1Entrez 유전자 요약


This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

OMIM-Description for 4E-BP1/EIF4EBP1OMIM-설명


inhibited the mTORC1 (601231) pathway in cells lacking EIF4EBP1, EIF4EBP2 (602224), and EIF4EBP3 (603483) and analyzed the effects on cell size, cell proliferation, and cell cycle progression. Although the EIF4EBPs had no effect on cell size, they inhibited cell proliferation by selectively inhibiting the translation of mRNAs that encode proliferation-promoting proteins and proteins involved in cell cycle progression. Thus, Dowling et al. (2010) concluded that control of cell size and cell cycle progression appear to be independent in mammalian cells, whereas in lower eukaryotes, EIF4E binding proteins influence both cell growth and proliferation.

.zh=위키피디아 요약4E-BP1/EIF4EBP1


EIF4EBP1

4E-BP1/EIF4EBP1 대체 이름

4E-BP1/EIF4EBP1 Related Products

4E-BP1/EIF4EBP1 Proteins

Product nameProduct name
휴먼 4E-BP1 / EIF4EBP1 단백질 (His 태그)

4E-BP1/EIF4EBP1 Antibodies

Product nameProduct name
4E-BP1 / EIF4EBP1 항체, 토끼 단클론항체4E-BP1 / EIF4EBP1 항체, 생쥐 단클론항체4E-BP1 / EIF4EBP1 항체, 생쥐 단클론항체4E-BP1 / EIF4EBP1 항체, 토끼 단클론항체4E-BP1 / EIF4EBP1 항체 (FITC), 생쥐 단클론항체4E-BP1 / EIF4EBP1 항체 (PE), 생쥐 단클론항체4E-BP1 / EIF4EBP1 항체, 토끼 다클론항체4E-BP1 / EIF4EBP1 항체, 토끼 단클론항체4E-BP1 / EIF4EBP1 항체, 토끼 다클론 항체, Antigen Affinity Purified

4E-BP1/EIF4EBP1 cDNA Clones

Product nameProduct name
휴먼 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-GFPSpark 태그휴먼 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-His 태그쥐 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-Myc 태그쥐 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-His 태그휴먼 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-GFPSpark 태그휴먼 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-Myc 태그휴먼 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-Flag 태그쥐 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-OFPSpark 태그쥐 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-OFPSpark 태그쥐 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-GFPSpark 태그휴먼 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-HA 태그휴먼 4E-BP1/EIF4EBP1 Gene ORF cDNA clone in cloning vector휴먼 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-HA 태그휴먼 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-OFPSpark 태그휴먼 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-OFPSpark 태그쥐 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-HA 태그쥐 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-Myc 태그휴먼 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-His 태그휴먼 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmidRat 4E-BP1/EIF4EBP1 Gene ORF cDNA clone in cloning vector쥐 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-HA 태그쥐 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-His 태그쥐 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-Flag 태그쥐 4E-BP1/EIF4EBP1 Gene ORF cDNA clone in cloning vector휴먼 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-Flag 태그쥐 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-Flag 태그쥐 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid쥐 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-GFPSpark 태그휴먼 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-Myc 태그

4E-BP1/EIF4EBP1 ELISA

Product nameProduct name
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