Aminoadipate aminotransferase  유전자

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RP300808 

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Aminoadipate aminotransferase Related Area

Aminoadipate aminotransferase 관련 경로

    Aminoadipate aminotransferase 요약 및 단백질 정보

    Aminoadipate aminotransferase 배경

    촉매 활성: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.; L-2-aminoadipate + 2-oxoglutarate = 2-oxoadipate + L-glutamate.
    보조 인자: Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; Evidence={ECO:0000269|PubMed:12126930, ECO:0000269|PubMed:18056995, ECO:0000269|PubMed:18056996};
    효소 조절: ENZYME REGULATION: Kynurenine transaminase activity is competitively inhibited by aminoadipate, asparagine, glutamate, histidine, cysteine, lysine, 3-hydroxy-kynurenine and phenylalanine. {ECO:0000269|PubMed:18620547}.
    하부단위 구조: Homodimer. {ECO:0000269|PubMed:18056995, ECO:0000269|PubMed:18056996, ECO:0000269|PubMed:18620547}.
    세포하 위치: Mitochondrion {ECO:0000305}.
    조직 특이성: Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary.
    염기서열 유사성: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. {ECO:0000305}.
    General information above from UniProt

    Aminoadipate aminotransferase 대체 이름

    KAT2,KATII, [homo-sapiens]
    Aadt,Kat2,KATII,mKat-2,AI875679, [mus-musculus]

    Aminoadipate aminotransferase 관련 연구

    주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".