ABCA3  유전자

All ABCA3 Reagents

Browse ABCA3 Products by

ABCA3 관련 경로

ABCA3 관련 제품

ABCA3 관련 제품

Featured Reagent Products

ABCA3 요약 및 단백질 정보

ABCA3 배경

도메인: Multifunctional polypeptide with two homologous halves, each containing a hydrophobic membrane-anchoring domain and an ATP binding cassette (ABC) domain (By similarity).
세포하 위치: Membrane; Multi-pass membrane protein (Potential).
조직 특이성: Highly expressed in lung, followed by brain, pancreas, skeletal muscle and heart. Weakly expressed in placenta, kidney and liver. Also expressed in medullary thyroid carcinoma cells (MTC) and in C-cell carcinoma.
질병과의 관련성: Pulmonary surfactant metabolism dysfunction 3 (SMDP3) [MIM:610921]: A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid- Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. Note=The disease is caused by mutations affecting the gene represented in this entry.
염기서열 유사성: Belongs to the ABC transporter superfamily. ABCA family.
Contains 2 ABC transporter domains.
General information above from UniProt

ABCA3 대체 이름

ABC3,ABC-C,SMDP3,LBM180,EST111653, [homo-sapiens]
Abc3,ABC-C,1810036E22Rik, [mus-musculus]

ABCA3 관련 연구

주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".