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ABCB9 요약 및 단백질 정보

ABCB9 배경

하부단위 구조: Homodimer.
도메인: The N-terminal region comprising the first four transmembrane domains is required for lysosomal localization but not for homodimerization or peptide transport.
세포하 위치: Lysosome membrane; Multi-pass membrane protein. Note=May be located in membrane rafts.
조직 특이성: Highly expressed in testis, and at moderate levels in brain, spinal cord, and thyroid. Not expressed in monocytes but strongly expressed during differentiation of monocytes to dendritic cells and macrophages.
유도: Not induced by interferon-gamma.
염기서열 유사성: Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
Contains 1 ABC transmembrane type-1 domain.
Contains 1 ABC transporter domain.
General information above from UniProt

ABCB9 대체 이름

TAPL,EST122234, [homo-sapiens]
TAPL,mKIAA1520, [mus-musculus]

ABCB9 관련 연구

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