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ABCF1  단백질

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    ABCF1 요약 및 단백질 정보

    ABCF1 배경

    하부단위 구조: Isoform 2 interacts (via N-terminus) with EIF2S1; the interaction is independent of its phosphorylated status. Isoform 2 associates (via both ABC transporter domains) with the ribosomes. {ECO:0000269|PubMed:17894550}.
    세포하 위치: Isoform 2: Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope.
    조직 특이성: Ubiquitous. {ECO:0000269|PubMed:9790762}.
    유도: By TNF in cultured synoviocytes.
    번역 후: Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2; inhibits association of EIF2 with ribosomes. {ECO:0000269|PubMed:17894550}.
    염기서열 유사성: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. {ECO:0000305}.; Contains 2 ABC transporter domains. {ECO:0000255|PROSITE-ProRule:PRU00434}.
    General information above from UniProt

    ABCF1 대체 이름

    ABC27,ABC50, [homo-sapiens]
    Abc50,GCN20,AU041969,D17Wsu166e, [mus-musculus]

    ABCF1 관련 연구

    주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".