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ABI2  ELISA Pair Set

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    ABI2 관련 제품

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    ABI2 요약 및 단백질 정보

    ABI2 배경

    하부단위 구조: Component of the WAVE1 complex composed of ABI2, CYFIP1 or CYFIP2, BRK1, NCKAP1 and WASF1/WAVE1. Within the complex, a heterdimer containing NCKAP1 and CYFIP1 interacts with a heterotrimer formed by WAVE1, ABI2 and BRK1. CYFIP2 binds to activated RAC1 which causes the complex to dissociate, releasing activated WASF1. The complex can also be activated by NCK1 (By similarity). Interacts with ABL1 and ABL2. {ECO:0000250, ECO:0000269|PubMed:21107423, ECO:0000269|PubMed:7590236, ECO:0000269|PubMed:8649853}.
    세포하 위치: Cytoplasm {ECO:0000250}.; Isoform 1: Cell projection, lamellipodium {ECO:0000250}. Cell projection, filopodium {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Isoform 1 but not isoform 3 is localized to protruding lamellipodia and filopodia tips. {ECO:0000250}.
    번역 후: Is a substrate for ABL1.
    염기서열 유사성: Belongs to the ABI family. {ECO:0000305}.; Contains 1 SH3 domain. {ECO:0000255|PROSITE-ProRule:PRU00192}.; Contains 1 t-SNARE coiled-coil homology domain. {ECO:0000255|PROSITE-ProRule:PRU00202}.
    General information above from UniProt

    ABI2 대체 이름

    ABI-2,ABI2B,AIP-1,AblBP3,argBP1,SSH3BP2,argBPIA,argBPIB, [homo-sapiens]
    AI839867,C130078H13,8430425M24Rik, [mus-musculus]

    ABI2 관련 연구

    주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".