The recombinant human ACYP2/GST chimera consists of 332 amino acids and has a predicted molecular mass of 38.2 kDa. It migrates as an approxiamtely 35 kDa band in SDS-PAGE under reducing conditions.
Lyophilized from sterile 20mM Tris, 0.15M NaCl, 2mM GSH, pH 7.5 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. 2. Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
ACYP2 Protein, Human, Recombinant (GST Tag): Alternative Names
ACYM Protein, Human; ACYP Protein, Human
ACYP2 Background Information
Recent genome-wide association studies have identified genetic variants in ACYP2 and WFS1 that are associated with cisplatin-induced ototoxicity. We sought to explore the role of these genetic susceptibility factors to cisplatin-induced ototoxicity in patients with testicular cancer. Telomere length, as a marker of biological aging, has been reported to influence the risk of several age-related diseases, including ischemic stroke. Recent studies have identified the genetic variant within ACYP2 and TSPYL6 associated with shorter telomere length. The research showed that that the G allele of rs1189664 and the A allele of rs12615793 within ACYP2 gene, rs12615793- smoking interaction, and rs1189664-alcohol drinking interaction were all associated with increased IS risk.
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