B7-H4 (Protein|Antibody|cDNA Clone|ELISA Kit)

All B7-H4 reagents are produced in house and quality controlled, including 3 B7-H4 Antibody, 27 B7-H4 Gene, 7 B7-H4 Lysate, 7 B7-H4 Protein, 2 B7-H4 qPCR. All B7-H4 reagents are ready to use.

Recombinant B7-H4 proteins are expressed by HEK293 Cells, Baculovirus-Insect Cells with fusion tags as C-His, C-mouse IgG1-Fc, C-human IgG1-Fc, C-cleavage.

B7-H4antibodies are validated with different applications, which are ELISA, IHC-P.

B7-H4cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each B7-H4 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

B7-H4 Protein (7)

Species

B7-H4 Protein, Human, Recombinant (His Tag)

10738-H08H

Expression host: HEK293 Cells

Human B7-H4/Vtcn1/B7S1 Protein 9077

B7-H4 Protein, Rat, Recombinant (His Tag)

81070-R08H

Expression host: HEK293 Cells

Rat B7-H4/Vtcn1/B7S1 Protein 17031

B7-H4 Protein, Human, Recombinant (Fc Tag)

10738-H02H

Expression host: HEK293 Cells

Human B7-H4/Vtcn1/B7S1 Protein 9076

B7-H4 Protein, Human, Recombinant (Fc Tag)

10738-H05H 

Expression host: HEK293 Cells

B7-H4 Protein, Human, Recombinant (Fc Tag)

10738-H05H

Expression host: HEK293 Cells

Human B7-H4/Vtcn1/B7S1 Protein 18576

B7-H4 Protein, Mouse, Recombinant (Fc Tag)

50017-M02H

Expression host: HEK293 Cells

Mouse B7-H4/Vtcn1/B7S1 Protein 11301

B7-H4 Protein, Mouse, Recombinant (His Tag)

50017-M08B

Expression host: Baculovirus-Insect Cells

Mouse B7-H4 Protein 19542
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B7-H4 Antibody (3)

Application Clonality
Host

Anti-B7-H4 Antibody

81070-T16

Application: ELISA

Clonality: PAb

Anti-B7-H4 Antibody

81070-T24

Application: ELISA,IHC-P

Clonality: PAb

Rat B7-H4/Vtcn1/B7S1 Immunohistochemistry(IHC) 18274

Anti-B7-H4 Antibody

10738-T24

Application: ELISA,IHC-P

Clonality: PAb

Human B7-H4/Vtcn1/B7S1 Immunohistochemistry(IHC) 7760
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B7-H4 cDNA Clone (27)

Human
Mouse
Rat

B7-H4 qPCR Primer (2)

B7-H4 Lysate (7)

V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type? membrane protein belonging to the B7 family of costimulatory proteins. These proteins are expressed on the surface of antigen-presenting cells and interact with ligands on T lymphocytes. They provide costimulatory signals that regulate T cell responses. A soluble form of B7H4 has also been detected. B7X / VTCN1 / B7H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, B7X / VTCN1 / B7H4 plays an important role, together with regulatory T-cells(Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. B7X / VTCN1 / B7H4 is also involved in promoting epithelial cell transformation. This membrane protein can be up-regulated by IL6 / interleukin-6 and IL10 / interleukin-10 and inhibited by CSF2 / GM-CSF and IL4 / interleukin-4 on antigen-presenting cells.

Immune Checkpoint
Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: IHC Antibodies
Immune Checkpoint Proteins
Immune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy

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