C8B  Protein, Antibody, ELISA Kit, cDNA Clone

C8B 관련 경로

    C8B 관련 제품

    C8B 관련 제품

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    C8B 요약 및 단백질 정보

    C8B 배경

    하부단위 구조: Heterotrimer of 3 chains: alpha, beta and gamma. The alpha and gamma chains are disulfide bonded. Component of the membrane attack complex (MAC). MAC assembly is initiated by protelytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and multiple copies of the pore-forming subunit C9.
    세포하 위치: Secreted.
    번역 후: N-glycosylated; contains one or two bound glycans. Not O- glycosylated.
    질병과의 관련성: Complement component 8 deficiency, 2 (C8D2) [MIM:613789]: A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
    염기서열 유사성: Belongs to the complement C6/C7/C8/C9 family.
    Contains 1 EGF-like domain.
    Contains 1 LDL-receptor class A domain.
    Contains 1 MACPF domain.
    Contains 2 TSP type-1 domains.
    General information above from UniProt

    C8B 대체 이름

    C8B 관련 연구

    주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".