CD98 (Protein|Antibody|cDNA Clone|ELISA Kit)

All CD98 reagents are produced in house and quality controlled, including 10 CD98 Antibody, 39 CD98 Gene, 1 CD98 IPKit, 4 CD98 Lysate, 4 CD98 Protein, 3 CD98 qPCR. All CD98 reagents are ready to use.

Recombinant CD98 proteins are expressed by HEK293 Cells with fusion tags as N-His, N-human IgG1-Fc.

CD98antibodies are validated with different applications, which are IHC-P, ELISA, WB, ICC/IF, IF, IP.

CD98cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD98 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

CD98 Protein (4)

Species

CD98 Protein, Mouse, Recombinant (His Tag)

50813-M07H

Expression host: HEK293 Cells

Mouse CD98/SLC3A2/4F2HC Protein 11924

CD98 Protein, Rat, Recombinant (Fc Tag)

80339-R01H

Expression host: HEK293 Cells

Rat CD98/SLC3A2/4F2HC Protein 6383

CD98 Protein, Rat, Recombinant (His Tag)

80339-R07H

Expression host: HEK293 Cells

Rat CD98/SLC3A2/4F2HC Protein 12576

CD98 Protein, Human, Recombinant (His Tag)

12206-H07H

Expression host: HEK293 Cells

Human CD98/SLC3A2/4F2HC Protein 10004
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CD98 Antibody (10)

Application Clonality
Host

Anti-CD98 Antibody

12206-R071

Application: IHC-P

Clonality: MAb

Human CD98/SLC3A2/4F2HC Immunohistochemistry(IHC) 3584

Anti-CD98 Antibody

12206-RP02

Application: WB,ELISA,IHC-P,IP

Clonality: PAb

Human CD98/SLC3A2/4F2HC Immunohistochemistry(IHC) 3583

Anti-CD98 Antibody

12206-RP01

Application: ELISA

Clonality: PAb

Anti-CD98 Antibody

50813-R048

Application: IHC-P

Clonality: MAb

Mouse CD98/SLC3A2/4F2HC Immunohistochemistry(IHC) 3181

Anti-CD98 Antibody

12206-R065

Application: ELISA

Clonality: MAb

Anti-CD98 Antibody

50813-R021

Application: ELISA

Clonality: MAb

Anti-CD98 Antibody

12206-MM04

Application: IHC-P

Clonality: MAb

Human CD98/SLC3A2/4F2HC Immunohistochemistry(IHC) 17559

Anti-CD98 Antibody

50813-RP01

Application: ELISA

Clonality: PAb

Anti-CD98 Antibody

50813-RP02

Application: WB,ELISA,IHC-P

Clonality: PAb

Mouse CD98/SLC3A2/4F2HC Immunohistochemistry(IHC) 3180
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CD98 cDNA Clone (39)

Rat
Human
Mouse

CD98 qPCR Primer (3)

CD98 IP Kit (1)

CD98 Lysate (4)

4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein which belongs to the SLC3A transporter family. SLC3A2 / MDU1 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. During gestation, expression in the placenta is significantly stronger at full-term than at the mid-trimester stage. SLC3A2 / MDU1 is expressed in HUVECS and at low levels in resting peripheral blood T-lymphocytes and quiescent fibroblasts. It is expressed in fetal liver and in the astrocytic process of primary astrocytic gliomas. SLC3A2 / MDU1 is also expressed in retinal endothelial cells and in the intestinal epithelial cell line Caco2-BBE. SLC3A2 / MDU1 is required for the function of light chain amino-acid transporters. It involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. SLC3A2 / MDU1 is involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7, SLC3A2 / MDU1 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. SLC3A2 / MDU1 plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. It is required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, SLC3A2 / MDU1 is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta.

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