Properdin  Protein, Antibody, ELISA Kit, cDNA Clone

Properdin Related Area

Properdin 관련 경로

    Properdin 요약 및 단백질 정보

    Properdin 배경

    하부단위 구조: In plasma, properdin exists as dimers, trimers or tetramers in the relative proportions of 26:54:20. {ECO:0000269|PubMed:15491616, ECO:0000269|PubMed:20382442}.
    도메인: TSP type-1 domains 0 and 6 bind to each other and mediate multimerization.
    세포하 위치: Secreted.
    질병과의 관련성: DISEASE: Properdin deficiency (PFD) [MIM:312060]: Results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III). {ECO:0000269|PubMed:10909851, ECO:0000269|PubMed:8871668, ECO:0000269|PubMed:9710744}. Note=The disease is caused by mutations affecting the gene represented in this entry.
    염기서열 유사성: Contains 7 TSP type-1 domains. {ECO:0000255|PROSITE-ProRule:PRU00210}.
    General information above from UniProt

    Properdin 대체 이름

    PFC,PROPERDIN,BFD,PFD, [homo-sapiens]
    Pfc,BCFG, [mus-musculus]

    Properdin 관련 연구

    주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".