CPN1  Protein, Antibody, ELISA Kit, cDNA Clone

CPN1 Related Area

CPN1 관련 경로

    CPN1 요약 및 단백질 정보

    CPN1 배경

    촉매 활성: Release of a C-terminal basic amino acid, preferentially lysine.
    보조 인자: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; ; Note=Binds 1 zinc ion per subunit.;
    하부단위 구조: Tetramer of two catalytic chains and two glycosylated inactive chains. {ECO:0000269|PubMed:17157876}.
    세포하 위치: Secreted, extracellular space.
    조직 특이성: Synthesized in the liver and secreted in plasma.
    질병과의 관련성: DISEASE: Carboxypeptidase N deficiency (CPND) [MIM:212070]: Patients affected present some combination of angioedema or chronic urticaria, as well as hay fever or asthma, and have also slightly depressed serum carboxy peptidase N, suggestive of autosomal recessive inheritance of this disorder. {ECO:0000269|PubMed:12560874}. Note=The disease is caused by mutations affecting the gene represented in this entry.
    염기서열 유사성: Belongs to the peptidase M14 family. {ECO:0000305}.
    General information above from UniProt

    CPN1 대체 이름

    CPN,SCPN, [homo-sapiens]
    CPN,0610011F20Rik, [mus-musculus]

    CPN1 관련 연구

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