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Carbonic Anhydrase II / Car2 Antibody, Rabbit MAb

데이터시트리뷰관련제품프로토콜
Mouse CA2 항체 제품 정보
면역원:Recombinant Mouse Carbonic Anhydrase II / CA2 protein (Catalog#50685-M08E)
Clone ID:003
면역글로불린(Ig) 유형:Rabbit IgG
농도:
내독소:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
제조방법:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Carbonic Anhydrase II / CA2 (rM Carbonic Anhydrase II / CA2; Catalog#50685-M08E; AAH55291.1; Met1-Lys260).
Mouse CA2 항체 사용 가이드
특이성:Mouse Carbonic Anhydrase II / CA2
적용:IHC-P

IHC-P: 1-10 μg/mL

보관:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Mouse CA2 Antibody IHC Application Image
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Caption:
Immunochemical staining of mouse CA2 in mouse brain with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
Carbonic Anhydrase II / Car2 Antibody, Rabbit MAb, Immunohistochemistry
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Caption:
Immunochemical staining of mouse CA2 in mouse intestine with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
Carbonic Anhydrase II / Car2 Antibody, Rabbit MAb, Immunohistochemistry
[이미지를 확대하려면 클릭]
Caption:
Immunochemical staining of mouse CA2 in mouse kidney with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
Carbonic Anhydrase II / Car2 Antibody, Rabbit MAb, Immunohistochemistry
[이미지를 확대하려면 클릭]
Caption:
Immunochemical staining of mouse CA2 in mouse stomach with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
Carbonic Anhydrase II / Car2 Antibody, Rabbit MAb, Immunohistochemistry
Other CA2 Antibody Products
Carbonic Anhydrase II 연구배경

The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase II is one of fourteen forms of human α carbonic anhydrases. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Renal carbonic anhydrase allows the reabsorption of sodium ions in the proximal tubule. Carbonic anhydrase II has been shown to interact with Band 3 and Sodium-hydrogen antiporter 1.

Mouse Carbonic Anhydrase II 참고자료
  • Lehtonen J, et al. (2004) Characterization of CA XIII, a Novel Member of the Carbonic Anhydrase Isozyme Family. The Journal of Biological Chemistry. 279: 2719-27.
  • Lindskog S. (1997) Structure and mechanism of carbonic anhydrase. Pharmacology & Therapeutics. 74(1):1-20.
  • Lilias A, et al. (1972) Crystal Structure of Human Carbonic Anhydrase C. Nature new biology. 235: 131-7.
  • Li XJ, et al. (2002) Carbonic Anhydrase II Binds to and Enhances Activity of the Na+/H+ Exchanger. The Journal of Biological Chemistry. 277: 36085-91.
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