휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone in cloning vector

    데이터시트리뷰관련제품프로토콜
    휴먼 CASP8/ALPS2B cDNA 클론 제품 정보
    Gene_bank_ref_id:NM_033355.3
    cDNA 크기:1440bp
    cDNA 설명:Full length Clone DNA of Homo sapiens caspase 8, apoptosis-related cysteine peptidase (CASP8), transcript variant B.
    유전자 동의어:Casp8, CAP4, MACH, MCH5, FLICE, ALPS2B, FLJ17672
    :Human
    벡터:pMD18-T Simple Vector
    Plasmid:pMD-Cas8
    제한 사이트:
    태그 씨퀀스:
    염기서열 설명:Identical with the Gene Bank Ref. ID sequence.
    Sequencing primers:M13-47 and RV-M
    ( We provide with CASP8 qPCR primers for gene expression analysis, HP100164 )
    Promoter:
    Application:
    Antibiotic in E.coli:Ampicillin
    Antibiotic in mammalian cell:
    Shipping_carrier:Each tube contains lyophilized plasmid.
    보관:The lyophilized plasmid can be stored at room temperature for three months.
    pMD18-T Simple Vector Information

    pMD18-T Simple Vector is a high-efficiency TA cloning vector constructed from pUC18, of which the initial multiple cloning sites (MCS) were destroyed. Thus the cDNA should be amplified by PCR with primers containing a restriction site for subclone. Competent cells appropriate for pUC18 are also appropriated for the Vector, e.g. JM109, DH5α, TOP10. The pMD18-T Simple Vector is 2.6kb in size. Selection of the plasmid in E. coli is conferred by the ampicillin resistance gene. The coding sequence was inserted by TA cloning at site 425.

    pMD18-T Simple Usage Suggestion

    The coding sequence can be amplified by PCR with M13-47 and RV-M primers.

    Vector Sequence Download
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone in cloning vector on other vectors
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone expression plasmid, C-GFPSpark 태그HG10078-ACG265260
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone expression plasmid, C-OFPSpark 태그HG10078-ACR265260
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone expression plasmid, N-GFPSpark 태그HG10078-ANG265260
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone expression plasmid, N-OFPSpark 태그HG10078-ANR265260
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone expression plasmid, C-Flag 태그HG10078-CF229890
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone expression plasmid, C-His 태그HG10078-CH229890
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone expression plasmid, C-Myc 태그HG10078-CM229890
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone expression plasmid, C-HA 태그HG10078-CY229890
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone expression plasmidHG10078-M-N229890
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone expression plasmid, N-Flag 태그HG10078-NF229890
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone expression plasmid, N-His 태그HG10078-NH229890
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone expression plasmid, N-Myc 태그HG10078-NM229890
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone expression plasmid, N-HA 태그HG10078-NY229890
    휴먼 CASP8/ALPS2B transcript variant B Gene ORF cDNA clone expression plasmidHG10078-UT229890
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    연구배경

    Caspase 8 is a cysteine dependent endoprotease that plays a key role in the regulation of apoptosis (also referred as programmed cell death), an event which is known to be essential in growth and development of embryo, and maintenance of tissue homeostasis. Caspases are broadly classified as apoptosis or inflammation regulatory caspases based on their role in respective processes. Of those known, caspase - 3, -6, -7, -8 and -9 are categorized as apoptotic caspases, whereas caspase -1, -4, -5 and -12 are grouped as inflammatory caspases. The apoptotic caspases are further classified into initiator caspases (caspase -8 and -9) and effecter caspases (caspase -3, -6 and -7) based on their role in transducing the apoptotic signals emanating at the cell membrane.

    Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

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    Cat No: HG10078-M
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