Anti-Cystatin C Antibody

Cat: 80040-R001
Contact us:
+86-400-890-9989
order@sinobiological.com
Distributors
All Cystatin C Reagents
CRO Services
Product recommended

All Cystatin C Reagents
Anti-Cystatin C Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-Cystatin C Antibody
Validated applications
IHC-P
Species reactivity
Reacts with: Rat
Specificity
Rat Cystatin C
Has cross-reactivity in ELISA with Mouse CST3
No cross-reactivity in ELISA with Human CST3
Immunogen
Recombinant Rat Cystatin C / CST3 protein (Catalog#80040-R08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Rat Cystatin C / CST3 (rR Cystatin C / CST3; Catalog#80040-R08H; P14841-1; Met1-Ala140).
Source
Monoclonal Rabbit IgG Clone #001
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Cystatin C Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
IHC-P 1:100-1:500  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Cystatin C Antibody (Rabbit Monoclonal antibody) Images
Rat Cystatin C / CST3 Immunohistochemistry(IHC) 3130
Immunochemical staining of rat CST3 in rat kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Rat Cystatin C / CST3 Immunohistochemistry(IHC) 3132
Immunochemical staining of rat CST3 in rat brain with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Cystatin C Background Information

Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal function, particularly to detect small reductions in glomerular filtration rate. The mature, active form of human cystatin C is a single non-glycosylated polypeptide chain consisting of 120 amino acid residues, with a molecular mass of 13,343-13,359 Da, and containing four characteristic disulfide-paired cysteine residues. Cystatin C is a low-molecular-weight protein which has been proposed as a marker of renal function that could replace creatinine. Indeed, the concentration of Cystatin C is mainly determined by glomerular filtration and is particularly of interest in clinical settings where the relationship between creatinine production and muscle mass impairs the clinical performance of creatinine. Since the last decade, numerous studies have evaluated its potential use in measuring renal function in various populations. More recently, other potential developments for its clinical use have emerged. In almost all the clinical studies, Cystatin C demonstrated a better diagnostic accuracy than serum creatinine in discriminating normal from impaired kidney function, but controversial results have been obtained by comparing this protein with other indices of kidney disease, especially serum creatinine-based equations, such as early atherosclerosis, Alzheimer's dementia, vascular aneurysms, hyperhomocysteinaemia and other neurodegenerative diseases. Cystatin C could be a useful clinical tool to identify HIV-infected persons. In addition, its expression is up-regulated in malignance of certain tumor progression.

Full Name
cystatin C
References
  • Mares J, et al. (2003) Use of cystatin C determination in clinical diagnostics. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 147(2): 177-80.
  • Mussap M, et al. (2004) Biochemistry and clinical role of human cystatin C. Crit Rev Clin Lab Sci. 41(5-6): 467-550.
  • Sronie-Vivien S, et al. (2008) Cystatin C: current position and future prospects. Clin Chem Lab Med. 46(12): 1664-86.
  • Taglieri N, et al. (2009) Cystatin C and cardiovascular risk. Clin Chem. 55(11): 1932-43.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Cystatin C Antibody Rabbit Polyclonal ELISA 80040-RP01
    Anti-Cystatin C Antibody Rabbit Polyclonal ELISA,IHC-P 80040-RP02
    Anti-Cystatin C Antibody Rabbit Monoclonal ELISA 80040-R002
    Anti-Cystatin C Antibody Rabbit Polyclonal WB,ELISA,IP 50239-RP02
    Anti-Cystatin C Antibody Rabbit Polyclonal ELISA 50239-RP01
    Anti-Cystatin C Antibody Rabbit Monoclonal ELISA 50239-R041
    Anti-Cystatin C Antibody Rabbit Monoclonal IHC-P 10439-R033
    Anti-Cystatin C Antibody Rabbit Polyclonal ELISA 10439-RP01
    Anti-Cystatin C Antibody Rabbit Polyclonal WB,ELISA,IP 10439-RP02
    Anti-Cystatin C Antibody Mouse Monoclonal ELISA(Cap) 10439-MM03
    Anti-Cystatin C Antibody Mouse Monoclonal ELISA(Det) 10439-MM06
    Anti-Cystatin C Antibody Mouse Monoclonal ELISA 10439-MM13
    Anti-Cystatin C Antibody Rabbit Monoclonal ELISA 10439-R001
    info info
    添加购物车成功! 添加购物车失败!