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Cystatin E / CST6 항체, 토끼 다클론 항체, Antigen Affinity Purified

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Mouse CST6 항체 제품 정보
면역원:Recombinant Mouse Cystatin-E / CST6 / Cystatin-M / Cystatin-6 protein (Catalog#50916-M08H)
Clone ID:
면역글로불린(Ig) 유형:Rabbit IgG
농도:
내독소:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
제조방법:Produced in rabbits immunized with purified, recombinant Mouse Cystatin-E / CST6 / Cystatin-M / Cystatin-6 (rM Cystatin-E / CST6 / Cystatin-M / Cystatin-6; Catalog#50916-M08H; NP_082899.1; Met1-Ala152). Cystatin-E / CST6 / Cystatin-M / Cystatin-6 specific IgG was purified by Mouse Cystatin-E / CST6 / Cystatin-M / Cystatin-6 affinity chromatography.
Mouse CST6 항체 사용 가이드
특이성:Mouse Cystatin-E / CST6 / Cystatin-M / Cystatin-6
적용:ELISA, IHC-P

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse Cystatin-E / CST6 / Cystatin-M / Cystatin-6. The detection limit for Mouse Cystatin-E / CST6 / Cystatin-M / Cystatin-6 is approximately 0.00975 ng/well.

IHC-P: 0.1-2 μg/mL

보관:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Mouse CST6 Antibody IHC Application Image
Cystatin E / CST6 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
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Caption:
Immunochemical staining of mouse CST6 in mouse skin with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
Other CST6 Antibody Products
Cystatin E / CST6 연구배경

Cystatin E/M, also referred to as CST6, is a member of type 2 cysteine proteinase inhibitors of the cystatin superfamily, and inhibits papain and cathepsin B. Cystatin E is a low molecular mass secreted protein existing in both a glycosylated (17 kDa) and an unglycosylated (14 kDa) form, with two characteristic intrachain disulfide bridges. Expression of cystatin M/E is found to be restricted to the epidermis, more specifically in the stratum granulosum, sweat glands, sebaceous glands, and the hair follicles. In addition to its function as a cysteine protease inhibitor, cystatin M/E also serves as a target for cross-linking by transglutaminases. Accordingly, cystatin M/E was suggested to be involved in barrier formation and maintenance. Furthermore, studies have revealed that cystatin M/E is frequently epigenetically inactivated during breast carcinogenesis, and thus be regarded as a candidate of tumour suppressor gene.

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Cat No: 50916-RP02-50
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All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
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