EFNB2A (Protein | Antibody | cDNA Clone | ELISA Kit)

All EFNB2A reagents are produced in house and quality controlled, including 2 EFNB2A Antibody, 13 EFNB2A Gene, 2 EFNB2A Lysate, 2 EFNB2A Protein. All EFNB2A reagents are ready to use.

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EFNB2A Related Research Area

EFNB2A Background

Efnb2a, also known as ephrin B2a, belongs to the ephrin family. Members of this family are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Efnb2a binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Efnb2a, together with ephb4 may play a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration.

EFNB2A References

  • Shaw KM. et al., 2006, Dev Dyn. 235 (7): 1753-60.
  • Kemp HA. et al., 2009, Dev Biol. 327 (2): 313-26.
  • Patten SA. et al., 2012, PLoS One. 7 (2): e31650.