IRTA1/FCRL4  Protein, Antibody, ELISA Kit, cDNA Clone

IRTA1/FCRL4 Related Area

IRTA1/FCRL4 관련 경로

    IRTA1/FCRL4 요약 및 단백질 정보

    IRTA1/FCRL4 배경

    세포하 위치: Cell membrane {ECO:0000269|PubMed:16157685, ECO:0000269|PubMed:16849395}; Single-pass type I membrane protein {ECO:0000269|PubMed:16157685, ECO:0000269|PubMed:16849395}.
    조직 특이성: Specifically expressed by memory and monocytoid B-cells which populate spleen and lymph nodes. Preferentially expressed in memory B-cells associated with mucosal tissue (at protein level). {ECO:0000269|PubMed:11290337, ECO:0000269|PubMed:11929751, ECO:0000269|PubMed:12881317, ECO:0000269|PubMed:16079106, ECO:0000269|PubMed:16157685, ECO:0000269|PubMed:16849395}.
    번역 후: Phosphorylated on cytoplasmic tyrosines upon activation. {ECO:0000269|PubMed:14597715}.
    질병과의 관련성: DISEASE: Note=A chromosomal aberration involving FCRL4 is found in non-Hodgkin lymphoma (NHG). Translocation t(1;1)(p36.3; q21.1-2).; DISEASE: Note=A chromosomal aberration involving FCRL4 is found in multiple myeloma (MM). Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.
    염기서열 유사성: Contains 4 Ig-like C2-type (immunoglobulin-like) domains. {ECO:0000305}.
    General information above from UniProt

    IRTA1/FCRL4 대체 이름

    IRTA1,CD307d,FCRH4,IGFP2, []

    IRTA1/FCRL4 관련 연구

    주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".