GGCT (Protein | Antibody | cDNA Clone | ELISA Kit)

All GGCT reagents are produced in house and quality controlled, including 3 GGCT Antibody, 30 GGCT Gene, 1 GGCT IP Kit, 1 GGCT Protein, 1 GGCT qPCR. All GGCT reagents are ready to use.

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GGCT Background

GGCT belongs to the gamma-glutamylcyclotransferase family. It catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism. GGCT may play a significant role in glutathione homeostasis. GGCT also induces release of cytochrome c from mitochondria with resultant induction of apoptosis. Pseudogenes of GGCT gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

GGCT References

  • Wagner SA. et al., 2011, Mol Cell Proteomics. 10 (10): M111.013284.
  • Kim W. et al., 2011, Mol Cell. 44 (2): 325-40.
  • Amano T. et al., 2012, J Histochem Cytochem. 60 (1): 76-86.