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혈구응집소 항체 & 단백질 (HA), H1N1 & H5N1

Swine H1N1 HA Specific & High Affinity Mabs,

Antibody ELISA Pairs Specific for Swine H1N1 at pg Detection Limit

Do Not Cross React with Seasonal Flu or Avian Flu

  

Bulk Order, Quotation, Question, E-mail to: Order@sinobiological.com

Hemagglutinin Antibody & Protein (HA)

  • Specific Antibodies
  • Cross-Reactive Antibodies
  • Hemagglutinin Protein

Hemagglutinin Antibody to H1N1 2009 Swine Flu (2)

Products Antigen Source
(CLICK for detailed Info. and Price)
Antigen
Molecule
Application Cat No
PAb Hemagglutinin Antibody to H1N1,
Rabbit Anti H1N1 PAb
HA WB, ELISA 11055-RP02
PAb Hemagglutinin Antibody to H1N1,
Rabbit Anti H1N1 PAb
HA WB, ELISA 11055-RP03

Hemagglutinin Antibody to H5N1 Avian Flu (3)

Products Antigen Source
(CLICK for detailed Info. and Price)
Antigen
Molecule
Application Cat No
MAb Hemagglutinin Antibody to H5N1 ,
Mouse Anti H5N1 MAb
HA WB 11048-MM10
MAb Hemagglutinin Antibody to H5N1,
Rabbit Anti H5N1 MAb
HA WB, ELISA 11048-RM08
PAb Hemagglutinin Antibody to H5N1,
Rabbit Anti H5N1 PAb
HA WB, ELISA 11048-RP02

Hemagglutinin Antibody to H9N2 (3)

Products Antigen Source
(CLICK for detailed Info. and Price)
Antigen
Molecule
Application Cat No
MAb Hemagglutinin Antibody to H9N2,
Mouse Anti H9N2 MAb
HA WB 11229-MM04
MAb Hemagglutinin Antibody to H9N2,
Mouse Anti H9N2 MAb
HA ELISA 11229-MM09
PAb Influenza Antibody to H9N2,
Rabbit Anti H9N2 PAb
HA WB, ELISA 11229-RP02

Hemagglutinin Antibody to Influenza B (3)

Products Antigen Source
(CLICK for detailed Info. and Price)
Antigen
Molecule
Application Cat No
MAb Influenza Antibody to Influenza B,
Mouse Anti Influenza B MAb
HA WB 11053-MM06
MAb Influenza Antibody to Influenza B,
Mouse Anti Influenza B MAb
HA ELISA 11053-MM09
PAb Hemagglutinin Antibody to Influenza B,
Rabbit Anti Influenza B PAb
HA WB, ELISA 11053-RP01

Hemagglutinin Antibody: Broad Cross-reactivity (23)

Products Antigen Source
(CLICK for detailed Info. and Price)
Antigen
Molecule
Application Cat No
MAb Influenza Antibody ,
Mouse Anti HA MAb
HA WB, ELISA 11055-MM01
MAb Influenza Antibody ,
Mouse Anti HA MAb
HA WB, ELISA 11055-MM04
MAb Influenza Antibody ,
Mouse Anti HA MAb
HA WB, ELISA 11055-MM09
MAb

Infleunza Antibody ,
Rabbit Anti HA MAb

HA WB, ELISA 11055-RM05
MAb Influenza Antibody ,
Rabbit Anti HA MAb
HA HI, WB, ELISA 11055-RM10
MAb Influenza Antibody ,
Mouse Anti HA MAb
HA WB, ELISA 11055-MM08
MAb Influenza Antibody,
Mouse Anti MAb
HA B/N, ELISA 11055-MM11
MAb Influenza Antibody ,
Rabbit Anti HA MAb
HA WB, ELISA 11055-RM06
PAb Influenza Antibody ,
Rabbit Anti HA PAb
HA WB, ELISA 11055-RP07
MAb Influenza Antibody ,
Rabbit Anti HA MAb
HA WB, ELISA 86001-RM01
MAb Influenza Antibody ,
Rabbit Anti HA MAb
HA WB, ELISA 86001-RM02
MAb Influenza Antibody ,
Rabbit Anti HA MAb
HA WB, ELISA 86001-RM03
MAb Influenza Antibody ,
Mouse Anti HA MAb
HA B/N, WB, ELISA 11048-MM01
MAb Influenza Antibody ,
Mouse Anti HA MAb
HA WB, ELISA 11048-MM03
MAb Influenza Antibody ,
Mouse Anti HA MAb
HA WB, ELISA 11048-MM04
MAb Influenza Antibody ,
Mouse Anti HA MAb
HA WB 11048-MM05
MAb Influenza Antibody ,
Mouse Anti HA MAb
HA ELISA 11048-MM06
MAb Influenza Antibody ,
Mouse Anti HA MAb
HA WB, ELISA 11048-MM11
MAb Influenza Antibody ,
Rabbit Anti HA MAb
HA B/N, WB, ELISA 11048-RM07
MAb Influenza Antibody ,
Rabbit Anti HA MAb
HA WB, ELISA 11048-RM09
MAb Influenza Antibody ,
Mouse Anti HA MAb
HA WB, ELISA 11056-MM03
MAb Influenza Antibody ,
Mouse Anti HA MAb
HA WB, ELISA 11056-MM05
MAb Influenza Antibody ,
Mouse Anti HA MAb
HA WB, ELISA 11229-MM15
MAb Influenza Antibody ,
Rabbit Anti HA MAb
HA WB, ELISA 11082-R019

Hemagglutinin Protein (1) H1N1, A/California/07/2009

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H1N1, A/California/07/2009
HA His Tag 11085-V08H

Hemagglutinin Protein (4) H1N1, A/California/04/2009

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H1N1,A/California/04/2009
HA His Tag 11055-V08H
Protein Influenza Hemagglutinin (HA)
H1N1, A/California/04/2009
HA, HA1, HA2 Partially cleaved, His Tag 11055-V08H2
Protein Influenza Hemagglutinin (HA)
H1N1, A/California/04/2009
HA1 HA1 Sub-unit, His Tag 11055-V08H4
Protein Influenza Hemagglutinin (HA)
H1N1, A/California/04/2009
HA His Tag 11055-V08B

Hemagglutinin Protein (2) H1N1, A/Brevig Mission/1/1918

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein

Influenza Hemagglutinin (HA)
H1N1, A/Brevig Mission/1/1918

HA His Tag 11068-V08H
Protein

Influenza Hemagglutinin (HA)
H1N1, A/Brevig Mission/1/1918

HA1 His Tag 11068-V08H1

Hemagglutinin Protein (2) H1N1, A/Brisbane/59/2007

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H1N1, A/Brisbane/59/2007
HA His Tag 11052-V08H
Protein Influenza Hemagglutinin (HA)
H1N1, A/Brisbane/59/2007
HA1 HA1 Sub-unit, His Tag 11052-V08H1

Hemagglutinin Protein (2) H1N1, A/New Caledonia/20/1999

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H1N1, A/New Caledonia/20/1999
HA His Tag 11683-V08H
Protein Influenza Hemagglutinin (HA)
H1N1, A/New Caledonia/20/1999
HA1 His Tag 11683-V08H1

Hemagglutinin Protein (2) H1N1, A/Puerto Rico/8/1934

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H1N1, A/Puerto Rico/8/1934
HA His Tag 11684-V08H
Protein Influenza Hemagglutinin (HA)
H1N1, A/Puerto Rico/8/1934
HA1 His Tag 11684-V08H1

Hemagglutinin Protein (2) H1N1, A/Ohio/UR06-0091/2007

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H1N1, A/Ohio/UR06-0091/2007
HA His Tag 11687-V08H
Protein Influenza Hemagglutinin (HA)
H1N1, A/Ohio/UR06-0091/2007
HA1 His Tag 11687-V08H1

Hemagglutinin Protein (2) H1N1, A/WSN/1933

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H1N1, A/WSN/1933
HA1 His Tag 11692-V08H1
Protein Influenza Hemagglutinin (HA)
H1N1, A/WSN/1933
HA His Tag 11692-V08H

Hemagglutinin Protein (2) H1N1, A/Solomon Islands/3/2006

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H1N1, A/Solomon Islands/3/2006
HA His Tag 11708-V08H
Protein Influenza Hemagglutinin (HA)
H1N1, A/Solomon Islands/3/2006
HA1 His Tag 11708-V08H1

Hemagglutinin Protein (3) H7N7, A/Netherlands/219/03

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H7N7, A/Netherlands/219/03
HA His Tag 11082-V08B
Protein Influenza Hemagglutinin (HA)
H7N7, A/Netherlands/219/03
HA His Tag 11082-V08H
Protein Influenza Hemagglutinin (HA)
H7N7, A/Netherlands/219/03
HA1 His Tag 11082-V08H1

Hemagglutinin Protein (2) H7N7, A/chicken/Netherlands/1/03

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H7N7, A/chicken/Netherlands/1/03
HA His Tag 11212-V08B
Protein Influenza Hemagglutinin (HA)
H7N7, A/chicken/Netherlands/1/03
HA1 His Tag 11212-V08H1

Hemagglutinin Protein (2) H3N2, A/Brisbane/10/2007

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H3N2, A/Brisbane/10/2007
HA His Tag 11056-V08H
Protein Influenza Hemagglutinin (HA)
H3N2, A/Brisbane/10/2007
HA1 His Tag 11056-V08H1

Hemagglutinin Protein (2) H3N2, A/Aichi/2/1968

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H3N2, A/Aichi/2/1968
HA His Tag 11707-V08H
Protein Influenza Hemagglutinin (HA)
H3N2, A/Aichi/2/1968
HA1 His Tag 11707-V08H1

Hemagglutinin Protein (2) H3N2, A/Wyoming/03/2003

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H3N2, A/Wyoming/03/2003
HA His Tag 11715-V08H
Protein Influenza Hemagglutinin (HA)
H3N2, A/Wyoming/03/2003
HA1 His Tag 11715-V08H1

Hemagglutinin Protein (2) H3N2, A/Wisconsin/67/X-161/2005

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H3N2, A/Wisconsin/67/X-161/2005
HA His Tag 11972-V08H
Protein Influenza Hemagglutinin (HA)
H3N2, A/Wisconsin/67/X-161/2005
HA1 His Tag 11972-V08H1

Hemagglutinin Protein (1) H2N2, A/Japan/305/1957

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H2N2, A/Japan/305/1957
HA His Tag 11088-V08H

Hemagglutinin Protein (2) H2N2, A/Canada/720/2005

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H2N2, A/Canada/720/2005
HA His Tag 11688-V08H
Protein Influenza Hemagglutinin (HA)
H2N2, A/Canada/720/2005
HA1 His Tag 11688-V08H1

Hemagglutinin Protein (2) Influenza B/Florida/4/2006

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
B/Florida/4/2006
HA His Tag 11053-V08H
Protein Influenza Hemagglutinin (HA)
B/Florida/4/2006
HA1 His Tag 11053-V08H1

Hemagglutinin Protein (2) Influenza B/Malaysia/2506/2004

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
B/Malaysia/2506/2004
HA His Tag 11716-V08H
Protein Influenza Hemagglutinin (HA)
B/Malaysia/2506/2004
HA1 His Tag 11716-V08H1

Hemagglutinin Protein (5) H5N1, A/Anhui/1/2005

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/Anhui/1/2005
HA His Tag 11048-V08H1
Protein Influenza Hemagglutinin (HA)
H5N1, A/Anhui/1/2005
HA1 HA1 Sub-unit, His Tag 11048-V08H2
Protein Influenza Hemagglutinin (HA)
H5N1, A/Anhui/1/2005
HA1, HA2 Cleaved, His Tag 11048-V08H4
Protein Influenza Hemagglutinin (HA)
H5N1, A/Anhui/1/2005
HA Mouse Fc-His 11048-V06H1
Protein Influenza Hemagglutinin (HA)
H5N1, A/Anhui/1/2005
HA1 Native 11048-VNAH2

Hemagglutinin Protein (2) H5N1, A/Vietnam/1203/2004

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/Vietnam/1203/2004
HA1 HA1 Sub-unit, Mouse Fc-His 10003-V06H1
Protein Influenza Hemagglutinin (HA)
H5N1, A/Vietnam/1203/2004
HA Mouse Fc-His 10003-V06H3

Hemagglutinin Protein (2) H5N1, A/Vietnam/1194/2004

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/Vietnam/1194/2004
HA His Tag 11062-V08H1
Protein Influenza Hemagglutinin (HA)
H5N1, A/Vietnam/1194/2004
HA1, HA2 Cleaved, His Tag 11062-V08H2

Hemagglutinin Protein (3) H5N1, A/bar-headed goose/Qinghai/14/2008

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1,A/bar-headed goose/Qinghai/14/2008
HA His Tag 11059-V08B1
Protein Influenza Hemagglutinin (HA)
H5N1,A/bar-headed goose/Qinghai/14/2008
HA His Tag 11059-V08H1
Protein Influenza Hemagglutinin (HA)
H5N1,A/bar-headed goose/Qinghai/14/2008
HA1, HA2 Cleaved, His Tag 11059-V08H2

Hemagglutinin Protein (2) H5N1, A/turkey/Turkey/1/2005

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/turkey/Turkey/1/2005
HA His Tag 11061-V08H1
Protein Influenza Hemagglutinin (HA)
H5N1, A/turkey/Turkey/1/2005
HA1, HA2 Cleaved, His Tag 11061-V08H2

Hemagglutinin Protein (2) H5N1, A/Indonesia/5/2005

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/Indonesia/5/2005
HA His Tag 11060-V08H1
Protein Influenza Hemagglutinin (HA)
H5N1, A/Indonesia/5/2005
HA, HA1, HA2 Partially cleaved , His Tag 11060-V08H2

Hemagglutinin Protein (1) H5N1, A/chicken/Egypt/2253-1/2006

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/chicken/Egypt/2253-1/2006
HA1 His Tag 11686-V08H1

Hemagglutinin Protein (2) H5N1, A/Hong Kong/483/97

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/Hong Kong/483/97
HA His Tag 11689-V08H
Protein Influenza Hemagglutinin (HA)
H5N1, A/Hong Kong/483/97
HA1 His Tag 11689-V08H1

Hemagglutinin Protein (2) H5N1, A/goose/Guiyang/337/2006

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/goose/Guiyang/337/2006
HA His Tag 11690-V08H
Protein Influenza Hemagglutinin (HA)
H5N1, A/goose/Guiyang/337/2006
HA1 His Tag 11690-V08H1

Hemagglutinin Protein (2) H5N1, A/Japanese white-eye/Hong Kong/1038/2006

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/Japanese white-eye/Hong Kong/1038/2006
HA His Tag 11694-V08H
Protein Influenza Hemagglutinin (HA)
H5N1, A/Japanese white-eye/Hong Kong/1038/2006
HA1 His Tag 11694-V08H1

Hemagglutinin Protein (2) H5N1, A/Egypt/2321-NAMRU3/2007

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/Egypt/2321-NAMRU3/2007
HA His Tag 11697-V08H
Protein Influenza Hemagglutinin (HA)
H5N1, A/Egypt/2321-NAMRU3/2007
HA1 His Tag 11697-V08H1

Hemagglutinin Protein (2) H5N1, A/duck/Hunan/795/2002

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/duck/Hunan/795/2002
HA His Tag 11698-V08H
Protein Influenza Hemagglutinin (HA)
H5N1, A/duck/Hunan/795/2002
HA1 His Tag 11698-V08H1

Hemagglutinin Protein (2) H5N1, A/Common magpie/Hong Kong/2256/2006

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/Common magpie/Hong Kong/2256/2006
HA His Tag 11700-V08H
Protein Influenza Hemagglutinin (HA)
H5N1, A/Common magpie/Hong Kong/2256/2006
HA1 His Tag 11700-V08H1

Hemagglutinin Protein (1) H5N1, A/duck/Laos/3295/2006

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/duck/Laos/3295/2006
HA1 His Tag 11701-V08H1

Hemagglutinin Protein (2) H5N1, A/Egypt/N05056/2009

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/Egypt/N05056/2009
HA His Tag 11702-V08H
Protein Influenza Hemagglutinin (HA)
H5N1, A/Egypt/N05056/2009
HA1 His Tag 11702-V08H1

Hemagglutinin Protein (1) H5N1, A/whooper swan/Mongolia/224/2005

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/whooper swan/Mongolia/224/2005
HA His Tag 11709-V08H

Hemagglutinin Protein (2) H5N1, A/Cambodia/R0405050/2007

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/Cambodia/R0405050/2007
HA His Tag 11710-V08H
Protein Influenza Hemagglutinin (HA)
H5N1, A/Cambodia/R0405050/2007
HA1 His Tag 11710-V08H1

Hemagglutinin Protein (2) H5N1, A/chicken/India/NIV33487/2006

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/chicken/India/NIV33487/2006
HA His Tag 11712-V08H
Protein Influenza Hemagglutinin (HA)
H5N1, A/chicken/India/NIV33487/2006
HA1 His Tag 11712-V08H1

Hemagglutinin Protein (2) H5N1, A/Hong kong/213/03

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/Hong kong/213/03
HA His Tag 11713-V08H
Protein Influenza Hemagglutinin (HA)
H5N1, A/Hong kong/213/03
HA1 His Tag 11713-V08H1

Hemagglutinin Protein (2) H5N1, A/Duck/Hong Kong/p46/97

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/Duck/Hong Kong/p46/97
HA His Tag 40001-V08H
Protein Influenza Hemagglutinin (HA)
H5N1, A/Duck/Hong Kong/p46/97
HA1 His Tag 40001-V08H1

Hemagglutinin Protein (2) H5N1, A/Xinjiang/1/2006

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N1, A/Xinjiang/1/2006
HA His Tag 40004-V08H
Protein Influenza Hemagglutinin (HA)
H5N1, A/Xinjiang/1/2006
HA1 His Tag 40004-V08H1

Hemagglutinin Protein (1) H9N2, A/Hong Kong/1073/1999

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Hemagglutinin (HA)
H9N2, A/Hong Kong/1073/1999
HA His Tag 11229-V08H

Hemagglutinin Protein (2) H9N2, A/Guinea fowl/Hong Kong/WF10/1999

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H9N2, A/Guinea fowl/Hong Kong/WF10/1999
HA His Tag 11719-V08H
Protein Influenza Hemagglutinin (HA)
H9N2, A/Guinea fowl/Hong Kong/WF10/1999
HA1 His Tag 11719-V08H1

Hemagglutinin Protein (2) H1N3, A/duck/NZL/160/1976

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Hemagglutinin (HA)
H1N3, A/duck/NZL/160/1976
HA His Tag 11685-V08H
Protein Hemagglutinin (HA)
H1N3, A/duck/NZL/160/1976
HA1 His Tag 11685-V08H1

Hemagglutinin Protein (2) H10N3, A/duck/Hong Kong/786/1979

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Hemagglutinin (HA)
H10N3, A/duck/Hong Kong/786/1979
HA His Tag 11693-V08H
Protein Hemagglutinin (HA)
H10N3, A/duck/Hong Kong/786/1979
HA1 His Tag 11693-V08H1

Hemagglutinin Protein (2) H1N2, A/swine/Guangxi/13/2006

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H1N2, A/swine/Guangxi/13/2006
HA His Tag 11703-V08H
Protein Influenza Hemagglutinin (HA)
H1N2, A/swine/Guangxi/13/2006
HA1 His Tag 11703-V08H1

Hemagglutinin Protein (2) H4N6, A/Swine/Ontario/01911-1/99

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H4N6, A/Swine/Ontario/01911-1/99
HA His Tag 11706-V08H
Protein Influenza Hemagglutinin (HA)
H4N6, A/Swine/Ontario/01911-1/99
HA1 His Tag 11706-V08H1

Hemagglutinin Protein (2) H4N6, A/mallard/Ohio/657/2002

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H4N6, A/mallard/Ohio/657/2002
HA His Tag 11714-V08H
Protein Influenza Hemagglutinin (HA)
H4N6, A/mallard/Ohio/657/2002
HA1 His Tag 11714-V08H1

Hemagglutinin Protein (2) H5N2, A/American green-winged teal/California/HKWF609/07

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N2, A/American green-winged teal/California/HKWF609/07
HA His Tag 11699-V08H
Protein Influenza Hemagglutinin (HA)
H5N2, A/American green-winged teal/California/HKWF609/07
HA1 His Tag 11699-V08H1

Hemagglutinin Protein (2) H5N3, A/duck/Hokkaido/167/2007

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N3, A/duck/Hokkaido/167/2007
HA His Tag 11696-V08H
Protein Influenza Hemagglutinin (HA)
H5N3, A/duck/Hokkaido/167/2007
HA1 His Tag 11696-V08H1

Hemagglutinin Protein (2) H5N8, A/duck/NY/191255-59/02

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H5N8, A/duck/NY/191255-59/02
HA His Tag 11717-V08H
Protein Influenza Hemagglutinin (HA)
H5N8, A/duck/NY/191255-59/02
HA1 His Tag 11717-V08H1

Hemagglutinin Protein (2) H6N1, A/northern shoveler/California/HKWF115/07

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H6N1, A/northern shoveler/California/HKWF115/07
HA His Tag 11723-V08H
Protein Influenza Hemagglutinin (HA)
H6N1, A/northern shoveler/California/HKWF115/07
HA1 His Tag 11723-V08H1

Hemagglutinin Protein (2) H8N4, A/pintail duck/Alberta/114/1979

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H8N4, A/pintail duck/Alberta/114/1979
HA His Tag 11722-V08H
Protein Influenza Hemagglutinin (HA)
H8N4, A/pintail duck/Alberta/114/1979
HA1 His Tag 11722-V08H1

Hemagglutinin Protein (2) H11N2, A/duck/Yangzhou/906/2002

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H11N2, A/duck/Yangzhou/906/2002
HA His Tag 11705-V08H
Protein Influenza Hemagglutinin (HA)
H11N2, A/duck/Yangzhou/906/2002
HA1 His Tag 11705-V08H1

Hemagglutinin Protein (2) H11N9, A/mallard/Alberta/294/1977

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H11N9, A/mallard/Alberta/294/1977
HA His Tag 11704-V08H
Protein Influenza Hemagglutinin (HA)
H11N9, A/mallard/Alberta/294/1977
HA1 His Tag 11704-V08H1

Hemagglutinin Protein (2) H12N5, A/green-winged teal/ALB/199/1991

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H12N5, A/green-winged teal/ALB/199/1991
HA His Tag 11718-V08H
Protein Influenza Hemagglutinin (HA)
H12N5, A/green-winged teal/ALB/199/1991
HA1 His Tag 11718-V08H1

Hemagglutinin Protein (2) H13N8, A/black-headed gull/Netherlands/1/00

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H13N8, A/black-headed gull/Netherlands/1/00
HA His Tag 11721-V08H
Protein Influenza Hemagglutinin (HA)
H13N8, A/black-headed gull/Netherlands/1/00
HA1 His Tag 11721-V08H1

Hemagglutinin Protein (2) H15N8, A/duck/AUS/341/1983

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H15N8, A/duck/AUS/341/1983
HA His Tag 11720-V08H
Protein Influenza Hemagglutinin (HA)
H15N8, A/duck/AUS/341/1983
HA1 His Tag 11720-V08H1

Hemagglutinin Protein (2) H16N3, A/black-heade

Products Source (CLICK for detailed Info. and Price) Molecule Description Cat No
Protein Influenza Hemagglutinin (HA)
H16N3, A/black-headed gull/Sweden/5/99
HA His Tag 11711-V08H
Protein Influenza Hemagglutinin (HA)
H16N3, A/black-headed gull/Sweden/5/99
HA1 His Tag 11711-V08H1

 

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Influenza Hemagglutinin Background

Influenza (flu) is a respiratory infection in mammals and birds. It is caused by an RNA virus in the family Orthomyxoviridae. The virus is divided into three main types (Influenza A, Influenza B, and Influenza C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA)). Influenza virus type A is found in a wide variety of bird and mammal species and can undergo major shifts in immunological properties. Influenza B is largely confined to humans and is an important cause of morbidity. Little is known about Influenza C, which is not an important source of morbidity.

Influenza A is further divided into subtypes based on differences in the membrane proteins hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. The notation HhNn is used to refer to the subtype comprising the hth discovered Hemagglutinin (HA) protein and the nth discovered neuraminidase (NA) protein. Influenza viruses that are known to infect human include the following sub-types. H1N1 virus that caused "Spanish Flu" (A/BrevigMission/1/1918(H1N1)) and seasonal flu (A/Brisbane/59/2007(H1N1), A/New Caledonia/20/1999(H1N1), and A/Solomon Islands/3/2006 (H1N1)) and a reassorted virus (A/California/04/2009(H1N1)) that caused the 2009 swine flu outbreak; H2N2 virus that caused the "Asian Flu"; H3N2 virus that caused the "Hong Kong Flu"; H5N1 "The Bird Flu" virus (A/Anhui/1/2005 (H5N1), A/Vietnam/1203/2004, A/Vietnam/1194/2004 (H5N1), A/bar-headed goose/Qinghai/14/2008 (H5N1), A/turkey/1/2005 (H5N1), A/Indonesia/5/2005 (H5N1)) that was the world's major influenza pandemic threat until the Swine Flu Pandemic of 2009; H7N7 virus that has unusual zoonotic potential; H1N2 is currently endemic in humans and pigs; and H9N2, H7N2, H7N3, H10N7 viruses.

The influenza viral Hemagglutinin (HA) protein is a homo trimer with a receptor binding pocket on the globular head of each monomer, and the influenza viral neuraminidase (NA) protein is a tetramer with an enzyme active site on the head of each monomer. Subtypes are further divided into strains; each genetically distinct virus isolate is usually considered to be a separate strain.

The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA0, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA0) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity.

The influenza virus neuraminidase (NA) protein is a second major surface antigen of the virion. Neuraminidase (NA) cleaves terminal sialic acid from glycoproteins or glycolipids. Thus, it functions to free virus particles from host cell receptors, to permit progeny virions to escape from the cell in which they arose, and so facilitate virus spread.

On April 29th 2009, the World Health Organization (WHO) announced that the rapid global spread of a new swine origin strain of influenza A (H1N1) virus (A/California/04/2009 (H1N1), A/California/06/2009 (H1N1), A/California/07/2009 (H1N1)) detected in the previous week warranted moving the global flu pandemic alert level to phase 5. Phase 5 indicates sustained human-to-human transmission of a novel influenza strain of animal origin in one WHO region of the world, and exported cases detected in other regions. Since its outbreak, the new swine influenza H1N1 virus has infected millions of people worldwide and hundreds of death. This new influenza outbreak is commonly referred to as the 2009 swine flu pandemic.

The highly pathogenic H5N1 avian influenza virus has become endemic in poultry in southeast Asia since 2003 and constitutes a major pandemic threat to humans. During 2004, H5N1 virus caused poultry disease in eight Asian countries and infected at least 44 persons, killing 32; most of these persons had had close contact with poultry.

Influenza virus vaccination is an effective approach to control influenza virus infection and pandemic spread of the virus. Each seasonal influenza vaccine contains hemagglutinin (HA) and neuraminidase antigen from three influenza subtype viruses-one subtype Influenza A H3N2 virus, one regular seasonal Influenza A H1N1 virus (not the 2009 H1N1 virus), and one Influenza B virus. Because of the influenza virus continues to mutate (antigen minor drifting or antigen major shifting) over time, the viruses in the vaccine change each year based on international surveillance and scientists' estimations about which types and strains of viruses will circulate in a given year. About 2 weeks after vaccination of the influenza viral antigen, antibodies that provide protection against influenza virus infection develop in the body.

Seasonal influenza virus vaccines are manufactured with a 50-year old egg-based process technology. Virus seed is injected into fertilized chicken eggs and incubated for several days to allow the virus to replicate and accumulate in the fluid surrounding the embryo. The virus fluid is collected from the inoculated eggs and harvested, purified, chemically inactivated and used to produce the vaccine.

Protection mechanism of influenza vaccine is well established to be neutralizing antibody (polyclonal human antibody) raised against influenza viral protein antigen such as the hemagglutinin (HA ) and neuraminidase (NA) protein antigen. Neutralizing antibody can block virus binding to host cells, block viral entry into host cells, and kill infected host cells. Recombinant monoclonal antibody (Mab, mouse monoclonal antibody, rabbit monoclonal antibody, chimeric monoclonal antibody, humanized monoclonal antibody) raised against the hemagglutinin (HA ) antigen or cloned from human B-cells (human monoclonal antibody) have shown to be promising anti-influenza infection product candidates.

Monoclonal or polyclonal antibody can be raised with peptide based antigen or protein based antigen. Antibody raised with protein based antigen could have better specificity and/or binding affinity than antibody raised with peptide based antigen, but cost associated with the recombinant protein antigen is usually higher. Anti influenza virus hemagglutinin (HA) monoclonal antibody or polyclonal antibody can be used for ELISA assay, western blotting detection, Immunohistochemistry (IHC), flow cytometry, neutralization assay, hemagglutinin inhibition assay, and early diagnosis of influenza viral infection.

Sino Biological is committed to use its expertise in recombinant protein and antibody development to provide solutions to support the influenza research community worldwide. Our solutions include contract service, recombinant hemagglutinin (HA) protein reagent, mouse and rabbit anti-hemagglutinin (HA) monoclonal antibody, anti-hemagglutinin (HA) polyclonal antibody, H1N1 hemagglutinin (HA) antibody pair (dual-set) for ELISA assay. All of our monoclonal or polyclonal antibody reagents are generated from immunization with recombinant hemagglutinin (HA) protein antigen, and hence should have better specificity and affinity than antibody raised from peptide based antigen. We are committed to develop innovative and cost-effective solutions. More influenza related protein and antibody reagents are coming.

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