CA5A cDNA ORF Clone, Human, N-HA tag General Information
Full length Clone DNA of Human carbonic anhydrase VA, mitochondrial with N terminal HA tag.
Enhanced CMV promoter
HA Tag Sequence: TATCCTTACGACGTGCCTGACTACGCC
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Antibiotic in Mammalian cell
Stable or Transient mammalian expression
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
CA5A cDNA ORF Clone, Human, N-HA tag Alternative Names
CA5 cDNA ORF Clone, Human;CA5AD cDNA ORF Clone, Human;CA5D cDNA ORF Clone, Human;Carbonic Anhydrase VA cDNA ORF Clone, Human;CAV cDNA ORF Clone, Human;CAVA cDNA ORF Clone, Human;GS1-21A4.1 cDNA ORF Clone, Human
CA5A Background Information
Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of the alpha-carbonic anhydrase family. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA5A / CA-VA is activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. It is inhibited by coumarins, sulfonamide derivatives such as acetazolamide and Foscarnet (phosphonoformate trisodium salt).
carbonic anhydrase VA, mitochondrial
Strausberg, R.L. et al., 2002, Proc. Natl. Acad. Sci. USA 99:16899 - 903. Liao, S.Y. et al., 2003, J. Med. Genet. 40:257 - 262. Temperini C.et al., 2006, Chemistry 12: 7057-66. Temperini C.et al., 2006, J. Med. Chem. 49: 3019-27. Supuran, C. T. et al., 2008, Curr Pharm Des. 14 (7): 601-602. Elleuche, S. et al., 2009, Curr Genet. 55 (2): 211-222.