휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid

    데이터시트리뷰관련제품프로토콜
    휴먼 CAMK4 cDNA 클론 제품 정보
    Gene_bank_ref_id:NM_001744.4
    cDNA 크기:1422bp
    cDNA 설명:Full length Clone DNA of Homo sapiens calcium/calmodulin-dependent protein kinase IV.
    유전자 동의어:CaMK-GR, MGC36771, CAMK4
    :Human
    벡터:pCMV3-untagged
    Plasmid:
    제한 사이트:
    태그 씨퀀스:
    염기서열 설명:
    Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
    ( We provide with CAMK4 qPCR primers for gene expression analysis, HP100632 )
    Promoter:Enhanced CMV mammalian cell promoter
    Application:Stable or Transient mammalian expression
    Antibiotic in E.coli:Ampicillin
    Antibiotic in mammalian cell:Hygromycin
    Shipping_carrier:Each tube contains lyophilized plasmid.
    보관:The lyophilized plasmid can be stored at room temperature for three months.
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid on other vectors
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid, C-GFPSpark 태그HG10664-ACG265260
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid, C-OFPSpark 태그HG10664-ACR265260
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid, N-GFPSpark 태그HG10664-ANG265260
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid, N-OFPSpark 태그HG10664-ANR265260
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid, C-Flag 태그HG10664-CF229890
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid, C-His 태그HG10664-CH229890
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid, C-Myc 태그HG10664-CM229890
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid, C-HA 태그HG10664-CY229890
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone in cloning vectorHG10664-M88420
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid, C-Flag 태그HG10664-M-F229890
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmidHG10664-M-N229890
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid, N-Flag 태그HG10664-NF229890
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid, N-His 태그HG10664-NH229890
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid, N-Myc 태그HG10664-NM229890
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmid, N-HA 태그HG10664-NY229890
    휴먼 CaM Kinase 4/CaMKIV Gene ORF cDNA clone expression plasmidHG10664-UT229890
     발현 벡터에 대해 자세히 알아보기
    Product nameProduct name
    연구배경

    Ca2+/ calmodulin-dependent protein kinase 4 (CAMKⅣ) belongs to the serine/threonine protein kinase family, and to the Ca2+/calmodulin-dependent protein kinase subfamily which is widely recognized as an essential enzyme implicated in the phophoinositide amplification cascade. Ca2+/calmodulin dependent protein kinase (CAMK) can be activated by the introcellular increased Ca2+ and then apt to combine with the target protein. Ca2+/ calmodulin-dependent protein kinase 4 (CAMKⅣ) is a multifunctional CaM-dependent kinase protein with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. All of the isforms of this family, including myosin light chain kinase, phosphorylase kinase, CaMK1, CaMKⅢ and CaMKⅣ have EF-hand structure.

    참고자료
  • Feliciano DM, et al. (2009) Repression of Ca2+/calmodulin-dependent protein kinase IV signaling accelerates retinoic acid-induced differentiation of human neuroblastoma cells. J Biol Chem. 284 (39): 26466-81.
  • Zhao X, et al. (2001). The modular nature of histone deacetylase HDAC4 confers phosphorylation-dependent intracellular trafficking. J Biol Chem. 276 (37): 35042-8.
  • Racioppi L, et al. (2008) Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller.
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    Cat No: HG10664-UT
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