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휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-His 태그

데이터시트리뷰관련제품프로토콜
Human GSTM2 cDNA 클론 제품 정보
Gene_bank_ref_id:NM_000848
cDNA 크기:657bp
cDNA 설명:Full length Clone DNA of Homo sapiens glutathione S-transferase mu 2 (muscle), transcript variant 1 with C terminal His tag.
유전자 동의어:GST4
:Human
벡터:pCMV3-C-His
Plasmid:
제한 사이트:
태그 씨퀀스:His Tag Sequence: CACCATCACCACCATCATCACCACCATCAC
염기서열 설명:
Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
Promoter:Enhanced CMV mammalian cell promoter
Application:Stable or Transient mammalian expression
Antibiotic in E.coli:Kanamycin
Antibiotic in mammalian cell:Hygromycin
Shipping_carrier:Each tube contains lyophilized plasmid.
보관:The lyophilized plasmid can be stored at room temperature for three months.
His Tag Info

A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.

Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokarfyotic expression systems.

휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-His 태그 on other vectors
휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-GFPSpark 태그HG12042-ACG265260
휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-OFPSpark 태그HG12042-ACR265260
휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-GFPSpark 태그HG12042-ANG265260
휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-OFPSpark 태그HG12042-ANR265260
휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag 태그HG12042-CF229890
휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-His 태그HG12042-CH229890
휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Myc 태그HG12042-CM229890
휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-HA 태그HG12042-CY229890
휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone in cloning vectorHG12042-G88420
휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Flag 태그HG12042-NF229890
휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-His 태그HG12042-NH229890
휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Myc 태그HG12042-NM229890
휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-HA 태그HG12042-NY229890
휴먼 GSTM2 transcript variant 1 Gene ORF cDNA clone expression plasmidHG12042-UT229890
 발현 벡터에 대해 자세히 알아보기
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연구배경

Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2 and GSTM2, is a cytoplasm protein which belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. Butyrate, an important luminal component produced from fermentation of dietary fibers, is an efficient inducer of GSTs and especially of GSTM2. Butyrate may act chemoprotectively by increasing detoxification capabilities in the colon mucosa.

참고자료
  • Campbell E, et al.,1990, J Biol Chem 265 (16): 9188-93. 
  • Vorachek WR, et al.,1991, Proc Natl Acad Sci USA. 88 (10): 4443-7.
  • Ebert,M.N. et al., 2003, Carcinogenesis. 24 (10):1637-44.
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    Cat No: HG12042-CH
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