GSTM2 cDNA ORF Clone, Human, C-His tag General Information
Full length Clone DNA of Human glutathione S-transferase mu 2 (muscle), transcript variant 1 with C terminal His tag.
Enhanced CMV promoter
His Tag Sequence: CACCATCACCACCATCATCACCACCATCAC
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Antibiotic in Mammalian cell
Stable or Transient mammalian expression
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
GSTM2 cDNA ORF Clone, Human, C-His tag Alternative Names
GST4 cDNA ORF Clone, Human;GSTM cDNA ORF Clone, Human;GSTM2-2 cDNA ORF Clone, Human;GTHMUS cDNA ORF Clone, Human
GSTM2 Background Information
Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2 and GSTM2, is a cytoplasm protein which belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. Butyrate, an important luminal component produced from fermentation of dietary fibers, is an efficient inducer of GSTs and especially of GSTM2. Butyrate may act chemoprotectively by increasing detoxification capabilities in the colon mucosa.
glutathione S-transferase mu 2 (muscle)
Campbell E, et al.,1990, J Biol Chem 265 (16): 9188-93. Vorachek WR, et al.,1991, Proc Natl Acad Sci USA. 88 (10): 4443-7. Ebert,M.N. et al., 2003, Carcinogenesis. 24 (10):1637-44.