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휴먼 IGF-1 / IGF-I / IGF1 단백질

데이터시트리뷰관련제품프로토콜
Human IGF1 단백질 제품 정보
동의어:IGF-1,IGF-I,IGF1A,IGFI,IGF‑I,MGF
단백질 구조:A DNA sequence encoding the human IGF1 (NP_001104754.1) (Gly49-Ala118) was expressed.
:Human
발현 숙주:Yeast
양식 및 배송:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Human IGF1 단백질 품질 관리 검사
순도:> 95 % as determined by SDS-PAGE
생리활성:Measured in a cell proliferation assay using MCF-7 cells. The ED50 for this effect is 9-36 ng/mL.
내독소:Please contact us for more information.
안정성:Samples are stable for up to twelve months from date of receipt at -70℃
예상된 N 말단(N Terminal):Gly 49
분자량:The recombinant human IGF1 consists 70 amino acids and predicts a molecular mass of 7.7 kDa.
Formulation:Lyophilized from sterile PBS,pH 7.4.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Human IGF1 단백질 사용 가이드
보관:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
복원:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Human IGF1 Protein SDS-PAGE
Human IGF-1 / IGF-I / IGF1 Protein

IGF1 관련 경로

    Other IGF1 Recombinant Protein Products
    IGF1/IGF‑I/IGF-1 연구배경

    IGF I, also known as mechano growth factor, somatomedin-C, IGF-I and IGF1, is a secreted protein which belongs to the?insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and II ( IGF-I and IGF-II ) and possibly the beta-subunit of 7S nerve growth factor, represents a group of structurally related polypeptides whose biological functions have diverged. The IGFs, or somatomedins, constitute a class of polypeptides that have a key role in pre-adolescent mammalian growth. IGF-I expression is regulated by GH and mediates postnatal growth, while IGF-II appears to be induced by placental lactogen during prenatal development. IGF1 / IGF-I may be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. IGF1 / IGF-I stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. Defects in IGF1 / IGF-I are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.

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    Cat No: 10598-HNAY-100
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    • Human IGF-1 / IGF-I / IGF1 Protein
      최근에 조회한 품목
      All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
      주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".