PDRG1 cDNA ORF Clone, Human, C-Myc tag General Information
Full length Clone DNA of Human p53 and DNA-damage regulated 1 with C terminal Myc tag.
Enhanced CMV promoter
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Antibiotic in Mammalian cell
Stable or Transient mammalian expression
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
PDRG1 cDNA ORF Clone, Human, C-Myc tag Alternative Names
C20orf126 cDNA ORF Clone, Human;PDRG cDNA ORF Clone, Human
PDRG1 Background Information
PDRG1, also known as C20orf126, belongs to the prefoldin subunit beta family. It is predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs. PDRG1 may play a role in chaperone-mediated protein folding. PDRG1 is overexpressed in tumors relative to normal tissues. Its expression is upregulated in multiple malignancies including cancers of the colon, rectum, ovary, lung, stomach, breast and uterus when compared to their respective matched normal tissues. Thus PDRG1 is a high-value novel tumor marker that could play a role in cancer development and/or progression.
p53 and DNA-damage regulated 1
Kim W. et al., 2011, Mol Cell. 44 (2): 325-40. Havugimana PC. et al., 2012, Cell. 150 (5): 1068-81. Jiang L. et al., 2011, Cancer Biol Ther. 11 (6): 567-73.