PLA2G2A cDNA ORF Clone, Human, untagged General Information
Identical with the Gene Bank Ref. ID sequence except for the point mutation 96 G/C not causing the amino acid variation.
Full length Clone DNA of Human phospholipase A2, group IIA (platelets, synovial fluid).
Enhanced CMV promoter
KpnI + XbaI (6.1kb + 0.44kb)
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Antibiotic in Mammalian cell
Stable or Transient mammalian expression
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
PLA2G2A cDNA ORF Clone, Human, untagged Validated Images
PLA2G2A cDNA ORF Clone, Human, untagged Alternative Names
MOM1 cDNA ORF Clone, Human;PLA2 cDNA ORF Clone, Human;PLA2B cDNA ORF Clone, Human;PLA2L cDNA ORF Clone, Human;PLA2S cDNA ORF Clone, Human;PLAS1 cDNA ORF Clone, Human;sPLA2 cDNA ORF Clone, Human
PLA2G2A Background Information
Phospholipase A2, membrane associated, also known as Phosphatidylcholine 2-acylhydrolase 2A, Group IIA phospholipase A2, Non-pancreatic secretory phospholipase A2 and PLA2G2A, is a peripheral membrane protein which belongs to the phospholipase A2 family. PLA2G2A is found in many cells and also extracellularly. The membrane-bound and secreted forms of PLA2G2A are identical. PLA2G2A has been proposed to play a role in anti-bacterial defense, inflammation and eicosanoid generation, in clearance of apoptotic cells, and in the Wnt signaling pathway. PLA2G2A is thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. PLA2G2A catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. PLA2G2A might be a factor in human colorectal tumorigenesis.
phospholipase A2, group IIA (platelets, synovial fluid)
Praml,C. et al., 1998, Oncogene. 17 (15):2009-12. Fijneman,R.J. et al., 2008,Front Biosci 13 :4144-74. Fijneman,R.J. et al., 2009, Cell Oncol 31 (5):345-56.