IL-11 / interleukin 11  Protein, Antibody, ELISA Kit, cDNA Clone

발현 숙주: E. coli  
50 µg 
5 µg 
20 µg 
10 µg 
Add to Cart
  • Slide 1
  • Slide 1
발현 숙주: E. coli  
50 µg 
5 µg 
100 µg 
10 µg 
Add to Cart
  • Slide 1

IL-11 / interleukin 11 Related Area

IL-11 / interleukin 11 관련 경로

    IL-11 / interleukin 11 관련 제품

    IL-11 / interleukin 11 요약 및 단백질 정보

    IL-11 / interleukin 11 배경

    하부단위 구조: Interacts with IL6ST and either IL11RA1 or IL11RA2, giving rise to a multimeric signaling complex. {ECO:0000269|PubMed:12919066, ECO:0000305|PubMed:12919066}.
    세포하 위치: Secreted {ECO:0000269|PubMed:1828438, ECO:0000269|PubMed:2145578}.
    염기서열 유사성: Belongs to the IL-6 superfamily. {ECO:0000305}.
    General information above from UniProt

    IL11 is a multifunctional cytokine first isolated in 1990 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation and could be use as a therapeutic for osteoporosis. IL11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. As a signaling molecule, IL11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; such functions include placentation and to some extent of decidualization.

    IL-11 / interleukin 11 대체 이름

    AGIF,IL-11, [homo-sapiens]
    interleukin 11,IL11,AGIF,IL-11,adipogenesis inhibitory factor,oprelvekin, [human]
    interleukin 11,Il11,IL-11, [mouse]
    IL-11, [mus-musculus]

    IL-11 / interleukin 11 관련 연구

  • McKinley D. et al., 1992, Genomics. 13 (3): 814-9.
  • Paul SR. et al., 1990, Proc Natl Acad Sci. 87 (19): 7512-6.
  • Kawashima I. et al., 1991, FEBS Lett. 283 (2): 199-202.
  • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".