All ILT4 reagents are produced in house and quality controlled, including 5 ILT4 Antibody, 13 ILT4 Gene, 3 ILT4 Lysate, 3 ILT4 Protein, 1 ILT4 qPCR. All ILT4 reagents are ready to use.
Recombinant ILT4 proteins are expressed by HEK293, HEK293 Cells with fusion tags as C-His, C-human IgG1-Fc.
ILT4antibodies are validated with different applications, which are ELISA, FCM.
ILT4cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each ILT4 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
ILT4, also known as LILRB2, is a member of the the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). ILT4 gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. Multiple transcript variants encoding different isoforms have been found for ILT4 gene. ILT4 is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.