After search, choose a molecule or a kind of categories listed in the left to narrow down your filter. If you have any problems, please contact us!

Text Size:AAA

인플루엔자 A H9N5 (A/shorebird/DE/261/2003) 헤마글루티닌(HA) 단백질 (His 태그)

데이터시트리뷰관련제품프로토콜
 HA 단백질 제품 정보
동의어:Hemagglutinin, HA
단백질 구조:A DNA sequence encoding the Influenza A virus (A/shorebird/DE/261/2003(H9N5)) hemagglutinin (ABB87950.1) (Met1-Lys523), termed as HA, was expressed with a polyhistidine tag at the C-terminus.
:H9N5
발현 숙주:Baculovirus-Insect Cells
양식 및 배송:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
 HA 단백질 품질 관리 검사
순도:> 95 % as determined by SDS-PAGE
생리활성:Measured by its ability to agglutinate guinea pig red blood cells.
HA titer is 0.02-0.1μg/mL for 1%GRBC
내독소:< 1.0 EU per μg protein as determined by the LAL method.
안정성:Samples are stable for up to twelve months from date of receipt at -70℃
예상된 N 말단(N Terminal):Asp 19
분자량:The recombinant hemagglutinin of Influenza A virus (A/shorebird/DE/261/2003(H9N5)) consists 516 amino acids and predicts a molecular mass of 58.3 kDa.
Formulation:Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
 HA 단백질 사용 가이드
보관:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
복원:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
 HA Protein SDS-PAGE
Influenza A H9N5 (A/shorebird/DE/261/2003) Hemagglutinin / HA Protein (His Tag)

HA 관련 경로

    Other HA Recombinant Protein Products
    HA 연구배경

    The influenza viral Hemagglutinin (HA) protein is a homo trimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of host endosomal membrane with the viral membrane.The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA0, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA0) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity.

     HA 참고자료
  • White JM, Hoffman LR, Arevalo JH, et al. (1997). "Attachment and entry of influenza virus into host cells. Pivotal roles of hemagglutinin". In Chiu W, Burnett RM, Garcea RL. Structural Biology of Viruses.
  • Suzuki Y (March 2005). "Sialobiology of influenza: molecular mechanism of host range variation of influenza viruses". Biol. Pharm. Bull. 28 (3): 399–408.
  • Senne DA, Panigrahy B, Kawaoka Y, et al. (1996). "Survey of the hemagglutinin (HA) cleavage site sequence of H5 and H7 avian influenza viruses: amino acid sequence at the HA cleavage site as a marker of pathogenicity potential". Avian Dis. 40 (2): 425–37
  • Product nameProduct name
    Size / Price
    Cat No: 40181-V08B-50
    정가: 
    가격:      (You Save: )
    Contact Us
    이미지
    • Influenza A H9N5 (A/shorebird/DE/261/2003) Hemagglutinin / HA Protein (His Tag)
      최근에 조회한 품목
        All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
        주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".