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인플루엔자 Matrix Protein 1 (M1)

Sino Biological은 헤마글루티닌(HA), 뉴라미니다제(NA), 핵단백질(NP), 기질 단백질 1(M1), NS1, NS2 등을 포함한 인플루엔자 A H1N1 항원들에 대해 종합적인 도구 세트(재조합 단백질, 항체, ELISA 키트, cDNA 클론)를 제공합니다.    

인플루엔자  Matrix Protein 1 (M1단백질, 항체, ELISA 분석 개발 서비스 and cDNA 클론 제품

M1 단백질M1 항체M1 ELISA 분석 개발 서비스M1 cDNA 클론
ProductMoleculeCat No.Package/Price 
인플루엔자 A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Matrix 단백질 1 / M1 단백질 (His 태그)M140010-V07E-10
40010-V07E-100
40010-V07E-50
10 µg/
100 µg/
50 µg/
Add to Cart
Add to Cart
Add to Cart
인플루엔자 A H7N9 (A/Anhui/1/2013) Matrix 단백질 1 / M1 단백질 (His 태그)M140107-V08E-10
40107-V08E-50
40107-V08E-100
10 µg/
50 µg/
100 µg/
Add to Cart
Add to Cart
Add to Cart
인플루엔자 A H1N1 (A/Brevig Mission/1/1918) Matrix 단백질 1 / M1 단백질 (His 태그)M140211-V07E-100
40211-V07E-50
100 µg/
50 µg/
Add to Cart
Add to Cart
인플루엔자 A H3N2 (A/Aichi/2/1968) Matrix 단백질 1 / M1 단백질 (His 태그)M140215-V07E-100
40215-V07E-50
100 µg/
50 µg/
Add to Cart
Add to Cart
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인플루엔자 Matrix Protein 1 (M1) 배경

Influenza virus matrix protein 1 (M1) has been shown to plays important roles during replication, assembly and budding of the virus. The M1 protein of influenza virus regulates the bi-directional transport of ribonucleoprotein (RNP) into and out of the nucleus. At the beginning of infection, the incoming RNP is transported into the nucleus only after detachment from M1, where RNP is involved in transcription/replication of the viral genome. In the late stage of infection, M1 inhibits viral RNA polymerase activity by binding to RNP, which may be a signal for RNP-transport from the nucleus to the cell surface. Finally, M1 mediates the association of RNP with viral envelope glycoproteins on the inner surface of the cytoplasmic membrane, which then promotes the virion formation and budding. The matrix protein M1, the organizer of assembly of influenza virus, interacts with other virus components and with cellular membranes. It has been proposed that M1 binding to lipids is mediated by its polybasic region. It been identified heat shock cognate protein 70 (Hsc70) is directly associated with M1 and therefore is required for viral production. The interactions of M1 with viral envelope proteins are essential to direct M1 to the plasma membrane for influenza virus particle release.

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