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인플루엔자 Nonstructural Protein 2 (NS2)

Sino Biological은 헤마글루티닌(HA), 뉴라미니다제(NA), 핵단백질(NP), 기질 단백질 1(M1), NS1, NS2 등을 포함한 인플루엔자 A H1N1 항원들에 대해 종합적인 도구 세트(재조합 단백질, 항체, ELISA 키트, cDNA 클론)를 제공합니다.    

인플루엔자  Nonstructural Protein 2 (NS2단백질, 항체, ELISA 분석 개발 서비스 and cDNA 클론 제품

NS2 단백질NS2 항체NS2 ELISA 분석 개발 서비스NS2 cDNA 클론
ProductMoleculeCat No.Package/Price 
인플루엔자 A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural 단백질 2 / NS2NS240012-VNAE-10
40012-VNAE-20
10 µg/
20 µg/
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인플루엔자 Nonstructural Protein 2 (NS2) 배경

The influenza virus non-structural protein NS2, which had no previously assigned function, was shown to mediate the nuclear export of virion RNAs by acting as an adaptor between viral ribonucleoprotein complexes and the nuclear export machinery of the cell. NS2, also called nuclear export protein (NEP), of influenza A virus contains a leucine-rich nuclear-export signal that could guide viral ribonucleoproteins to cross the nuclear pore complex (NPC) and complete directional nucleocytoplasmic trafficking. The NS2 (NEP) protein contains a highly conserved nuclear export signal (NES) motif in its amino-terminal region (12ILMRMSKMQL21, A/WSN/33), which is thought to be required for nuclear export of viral ribonucleoprotein complexes (vRNPs) mediated by a cellular export factor, CRM1. The NS2 is a phosphoprotein and binds to the nucleoporin yRip1 and Rab/hRip as well as the M1 protein which associates with the vRNPs. Therefore, the NS2 protein plays an important role in the nuclear export of the vRNPs.

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