Anti-Cytokeratin 5 / KRT5 Antibody

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Anti-Cytokeratin 5 / KRT5 Antibody (Rabbit Polyclonal antibody) General Information

Product name
Anti-Cytokeratin 5 / KRT5 Antibody
Validated applications
WB
Species reactivity
Reacts with: Human
Specificity
Human Cytokeratin 5 / KRT5
Immunogen
A synthetic peptide corresponding to the center region of the human KRT5
Preparation
Produced in rabbits immunized with A synthetic peptide corresponding to the center region of the human KRT5 , and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Cytokeratin 5 / KRT5 Antibody (Rabbit Polyclonal antibody) Validated Applications

Application Dilution
WB 1:1000-1:5000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Cytokeratin 5 / KRT5 Antibody (Rabbit Polyclonal antibody) Images

Anti-KRT5 rabbit polyclonal antibody at 1:1000 dilution

Lane A: HCT116 Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:62 kDa

Observed band size:55 kDa

Anti-Cytokeratin 5 / KRT5 Antibody: Alternative Names

Anti-CK5 Antibody; Anti-DDD Antibody; Anti-DDD1 Antibody; Anti-EBS2 Antibody; Anti-K5 Antibody; Anti-KRT5A Antibody

Cytokeratin 5 / KRT5 Background Information

Keratin 5 is the major type II keratin of the basal cells of epidermis and of other stratified epithelia. With its type I partner, keratin 14, it constitutes a major fraction of the cytoskeleton of the basal cells. Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP) is a rare dermatologic disorder of autosomal dominant inheritance with intraepidermal blistering after minor trauma, reticular hyperpigmentation unrelated to the blistering, nail dystrophy, and mild palmoplantar keratosis. Keratin 5 and keratin 14 are known to be essential for the basal keratinocyte cytoskeleton and are defective in several forms of epidermolysis bullosa simplex. Recently, a 71C-->T transition in the keratin 5 gene (KRT5) causing a P24L substitution was identified in some patients with EBS-MP.
Full Name
keratin 5, type II

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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