L-FABP: L-FABP Protein | L-FABP Antibody

L-FABP Gene family

L-FABP Background

Fatty acid-binding protein, liver, also known as Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, FABP1 and FABPL,is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP1 and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. FABP1 / FABPL binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. It forms a beta-barrel structure that accommodates hydrophobic ligands in its interior. FABP1 / FABPL may be involved in intracellular lipid transport.

Reference for L-FABP

  • Chen SH, et al.,1986,Somat Cell Mol Genet12(3): 303-6.
  • Weickert MO, et al.,2007, Am J Physiol Endocrinol Metab. 293(4): E1078-84.
  • Noiri,E. et al., 2009, Am J Physiol Renal Physiol296(4):F669-79.
  • Fisher,E. et al., 2007, Mol Genet Metab. 91(3):278-84.

L-FABP Protein

L-FABP protein function

Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes (PubMed:25732850). Binds cholesterol (PubMed:25732850). Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity). {ECO:0000250|UniProtKB:P82289, ECO:0000269|PubMed:25732850}.

L-FABP protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    127.00
  • Mass (Da)
    14.00

L-FABP Antibody

There are 2 L-FABP antibodies which are validated in multiple tissues with various applications, including WB, IHC-P. There are 2 L-FABP antibody for WB, 1 L-FABP antibody for IHC-P. Among all these L-FABP antibodies, there are 1 anti-L-FABP mouse monoclonal antibodies , 1 anti-L-FABP rabbit polyclonal antibodies . All the L-FABP anbodies are produced in house and all are in stock. L-FABP antibody customerized service is available.

L-FABP Gene

FABP1 gene / cDNA is a protein-coding gene which located on 2p11.2. The FABP1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, and frog.220 organisms have orthologs with human gene FABP1.