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LFA-3 / CD58  단백질

All LFA-3 Reagents

발현 숙주: Human Cells  
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12409-H02H-50
12409-H02H-100
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발현 숙주: Human Cells  
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12409-H08H-50
12409-H08H-100
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발현 숙주: Human Cells  
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90190-C08H-50
90190-C08H-100
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LFA-3 / CD58 관련 경로

    LFA-3 / CD58 관련 제품

    LFA-3 / CD58 관련 제품

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    LFA-3 / CD58 요약 및 단백질 정보

    LFA-3 / CD58 배경

    유전자 요약: This gene encodes a member of the immunoglobulin superfamily. LFA-3 is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. LFA-3 is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
    General information above from NCBI
    하부단위 구조: Interacts with CD2.
    세포하 위치: Isoform 1: Cell membrane; Single-pass type I membrane protein.
    Isoform 2: Cell membrane; Lipid-anchor, GPI- anchor.
    염기서열 유사성: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.C
    General information above from UniProt

    CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.

    LFA-3 / CD58 대체 이름

    LFA3, [Cynomolgus]
    ag3,CD58,CD58 antigen,CD58 molecule,LFA3,LFA-3,lymphocyte function-associated antigen 3,RP5-1086K13.2,surface glycoprotein LFA-3, [human]

    LFA-3 / CD58 관련 연구

  • Rochelle JM. et al., 1993, Int Immunol. 5 (2): 209-16.
  • Virtaneva KI. et al., 1993, Immunogenetics. 37 (6): 461-5.
  • Horejsí V. et al., 1991, FEBS Lett. 288 (1-2): 1-4.
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