ERK1 / MAPK3 (Protein | Antibody | cDNA Clone | ELISA Kit)

All ERK1 / MAPK3 reagents are produced in house and quality controlled, including 1 ERK1 / MAPK3 Antibody, 15 ERK1 / MAPK3 Gene, 1 ERK1 / MAPK3 IP Kit, 1 ERK1 / MAPK3 qPCR. All ERK1 / MAPK3 reagents are ready to use.

ERK1 / MAPK3 Background

The protein encoded by ERK1 gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

ERK1 / MAPK3 References

  • Kolb RH, Greer PM, Cao PT, Cowan KH, Yan Y. ERK1/2 Signaling Plays an Important Role in Topoisomerase II Poison-Induced G2/M Checkpoint Activation. Tan M, ed. PLoS ONE. 2012;7(11):e50281.