MFI2: MFI2 Protein | MFI2 Antibody

MFI2 Gene family

MFI2 Background

The long non-coding RNA MFI2 antisense RNA is overexpressed in human cancer tissues and its increased expression is associated with occurrence and metastasis of cancer.lncRNA MFI2 could promote proliferation and migration of osteosarcoma cells by regulating FOXP4 expression, which suggested critical roles of lncRNA MFI2 and FOXP4 in occurrence and development of human osteosarcoma.

Reference for MFI2

  • Richardson DR. (2000) The role of the membrane-bound tumour antigen, melanotransferrin (p97), in iron uptake by the human malignant melanoma cell. Eur J Biochem. 267(5): 1290-8.
  • Kim DK, et al. (2001) Serum melanotransferrin, p97 as a biochemical marker of Alzheimer's disease. Neuropsychopharmacology. 25(1): 84-90.
  • Rothenberger S, et al. (1996) Coincident expression and distribution of melanotransferrin and transferrin receptor in human brain capillary endothelium. Brain Res. 712(1): 117-21.
  • Baker EN, et al. (1992) Human melanotransferrin (p97) has only one functional iron-binding site. FEBS Lett. 298(2-3): 215-8.

MFI2 Protein

MFI2 protein function

Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.

MFI2 protein expression

Tissue specificity

Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts.

MFI2 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (Da)

MFI2 Antibody

There are 2 MFI2 antibodies which are validated in multiple tissues with various applications, including ELISA. There are 2 MFI2 antibody for ELISA. Among all these MFI2 antibodies, there are 1 anti-MFI2 rabbit monoclonal antibodies , 1 anti-MFI2 rabbit polyclonal antibodies . All the MFI2 anbodies are produced in house and all are in stock. MFI2 antibody customerized service is available.

MFI2 Gene

MELTF gene / cDNA is a protein-coding gene which located on 3q29. The MELTF gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, and frog.226 organisms have orthologs with human gene MELTF.