All CXCL7 reagents are produced in house and quality controlled, including 5 CXCL7 Antibody, 52 CXCL7 Gene, 1 CXCL7 IPKit, 2 CXCL7 Lysate, 7 CXCL7 Protein, 3 CXCL7 qPCR. All CXCL7 reagents are ready to use.
Recombinant CXCL7 proteins are expressed by E. coli, HEK293 Cells, Yeast with fusion tags as N-His, N-mouse IgG1-Fc, C-His, N-human IgG1-Fc.
CXCL7antibodies are validated with different applications, which are ELISA, WB, IP.
CXCL7cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CXCL7 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Pro-platelet basic protein (PPBP) is also known as Chemokine (C-X-C motif) ligand 7 (CXCL7) and nucleosome assembly protein (Nap-2). Nap-2 / PPBP / CXCL7 is released in large amounts from platelets following their activation and is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. Nap-2 / PPBP / CXCL7 has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Nap-2 is a ligand for CXCR1 and CXCR2, and Nap-2, Nap-2 (73), Nap-2 (74), Nap-2 (1-66), and most potent Nap-2 (1-63) are chemoattractants and activators for neutrophils.