NGF / NGFB 항체, 토끼 단클론항체

데이터시트리뷰관련제품프로토콜
Human NGF 항체 제품 정보
면역원:Recombinant Human NGF / NGFB protein (Catalog#11050-HNAC)
Clone ID:D03
면역글로불린(Ig) 유형:Rabbit IgG
농도:
내독소:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
제조방법:This antibody was obtained from a rabbit immunized with purified, recombinant Human NGF / NGFB (rh NGF / NGFB; Catalog#11050-HNAC; NP_002497.2; Ser122-Arg239).
Human NGF 항체 사용 가이드
특이성:Human NGF / NGFB
적용:IHC-P

IHC-P: 5-20 μg/mL

보관:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Human NGF Antibody IHC Application Image
NGF / NGFB Antibody, Rabbit MAb, Immunohistochemistry
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Caption:
Immunochemical staining of human β-NGF in human brain (from 2 donors) with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
Other NGF Antibody Products
NGF/NGFB/beta-NGF 연구배경

Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. In addition, previous studies indicated that NGF may also have an important role in the regulation of the immune system.

Human NGF/NGFB/beta-NGF 참고자료
  • Castellanos MR, et al. (2003) Evaluation of the neurorestorative effects of the murine beta-nerve growth factor infusions in old rat with cognitive deficit. Biochem Biophys Res Commun. 312(4): 867-72.
  • Wang TH, et al. (2008) Effects of pcDNA3-beta-NGF gene-modified BMSC on the rat model of Parkinson's disease. J Mol Neurosci. 35(2): 161-9.
  • Perrard MH, et al. (2009) Redundancy of the effect of TGFbeta1 and beta-NGF on the second meiotic division of rat spermatocytes. Microsc Res Tech. 72(8): 596-602.
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    Cat No: 11050-RD03-50
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    • NGF / NGFB Antibody, Rabbit MAb, Immunohistochemistry
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