RAB7A (Protein | Antibody | cDNA Clone | ELISA Kit)

All RAB7A reagents are produced in house and quality controlled, including 3 RAB7A Antibody, 60 RAB7A Gene, 1 RAB7A IP Kit, 1 RAB7A Protein, 2 RAB7A qPCR. All RAB7A reagents are ready to use.

RAB7A Background

RAB7A is a ubiquitous small GTPase, which controls transport to late endocytic compartments. Silencing or overexpression of wild type RAB7A changed the soluble/insoluble rate of peripherin indicating that RAB7A is important for peripherin organization and function. In addition, disease-causing RAB7A mutant proteins bind more strongly to peripherin and their expression causes a significant increase in the amount of soluble peripherin. The altered interaction between disease-causing RAB7A mutants and peripherin could play an important role in CMT2B neuropathy.