REG3A 항체, 토끼 단클론항체

데이터시트리뷰관련제품프로토콜
Human REG3A 항체 제품 정보
면역원:Recombinant Human REG3A protein (Catalog#11235-H08H)
Clone ID:019
면역글로불린(Ig) 유형:Rabbit IgG
농도:
내독소:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
제조방법:This antibody was obtained from a rabbit immunized with purified, recombinant Human REG3A (rh REG3A; Catalog#11235-H08H; Q06141-1; Met 1-Asp 175).
Human REG3A 항체 사용 가이드
특이성:Human REG3A
No cross-reactivity in ELISA with
Human REG3G
Mouse REG3A
Human REG1B
적용:ELISA, IHC-P

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human REG3A. The detection limit for Human REG3A is approximately 0.039 ng/well.

IHC-P: 1-10 μg/mL

보관:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Human REG3A Antibody IHC Application Image
REG3A Antibody, Rabbit MAb, Immunohistochemistry
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Caption:
Immunochemical staining of human REG3A in human pancreatic carcinoma with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
REG3A Antibody, Rabbit MAb, Immunohistochemistry
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Caption:
Immunochemical staining of human REG3A in human small intestine with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
Other REG3A Antibody Products
REG3A 연구배경

Regenerating islet-derived protein 3-alpha, also known as Regenerating islet-derived protein III-alpha, REG-3-alpha, REG3A, and HIP, is secreted protein which contains one C-type lectin domain. REG3A is constitutively expressed in intestine, and is a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It is overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. REG3A is also a stress protein involved in the control of bacterial proliferation. REG3A is down-regulated in most primary human gastric cancer cells, and might be useful in the diagnosis of gastric cancer. Additionally, REG3A is a target of beta-catenin signaling in Huh7 hepatoma cells. The REG1A and REG3A are downstream targets of the Wnt pathway during liver tumorigenesis.

Human REG3A 참고자료
  • Cavard C, et al. (2006) Overexpression of regenerating islet-derived 1 alpha and 3 alpha genes in human primary liver tumors with beta-catenin mutations. Oncogene. 25(4): 599-608.
  • Choi B, et al. (2007) Downregulation of regenerating islet-derived 3 alpha (REG3A) in primary human gastric adenocarcinomas. Exp Mol Med. 39(6): 796-804.
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    Cat No: 11235-R019-50
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