ST6GAL1 / ST6GAL-I 항체, 토끼 단클론항체

    데이터시트리뷰관련제품프로토콜
    휴먼 ST6GAL1 항체 제품 정보
    면역원:Recombinant Human ST6GAL1 / ST6GAL-I protein (Catalog#11590-H07H)
    Clone ID:117
    면역글로불린(Ig) 유형:Rabbit IgG
    농도:
    내독소:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    제조방법:This antibody was obtained from a rabbit immunized with purified, recombinant Human ST6GAL1 / ST6GAL-I (rh ST6GAL1 / ST6GAL-I; Catalog#11590-H07H; P15907; Lys27-Cys406).
    Other ST6GAL1 Antibody Products
    반응성: Human  
    신청: ELISA  
      11590-MM05-50
      11590-MM05-200
      11590-MM05-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      반응성: Human  
      신청: IHC-P  
      • Slide 1
      • Slide 1
      11590-R036-50
      11590-R036-100
      50 µg 
      100 µg 
      Add to Cart
      반응성: Human  
      신청: 
        11590-R001-50
        11590-R001-100
        11590-R001-1
        50 µg 
        100 µg 
        1 mg 
        Add to Cart
        반응성: Human  
        신청: ELISA  
          11590-RP01-400
          11590-RP01-200
          11590-RP01-100
          400 µg 
          200 µg 
          100 µg 
          Add to Cart
          반응성: Human  
          신청: ELISA  WB  IP  
          • Slide 1
          • Slide 1
          11590-RP02-50
          11590-RP02-200
          11590-RP02-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          ST6GAL1/ST6GAL-I 연구배경

          Beta-galactoside alpha-2,6-sialyltransferase 1, also known as B-cell antigen CD75, Sialyltransferase 1, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6GAL1 and SIAT1, is a single-pass type II membrane protein which belongs to the glycosyltransferase 29 family. Sialyltransferases are key enzymes in the biosynthesis of sialoglycoconjugates that catalyze the transfer of sialic residue from its activated form to an oligosaccharidic acceptor. ST6GAL1 / SIAT1 is normally found in the?Golgi?but which can be proteolytically processed to a soluble form. It is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. β-Galactoside α2,6-sialyltransferases ST6GAL1 and ST6GAL2 are the two unique members of the ST6GAL family described in higher vertebrates. ST6GAL1 / SIAT1 transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.

          휴먼 ST6GAL1/ST6GAL-I 참고자료
        • Collins,B.E. et al., 2006, Nat Immunol. 7(2):199-206.
        • Videira,P.A. et al., 2008, Glycoconj J. 25(3): 259-68.
        • Petit,D. et al., 2010, J Biol Chem. 285(49): 38399-414.
        • Kroes,R.A. et al., 2010, Proc Natl Acad Sci USA.107(28):12646-51.
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