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ST6GAL1 / ST6GAL-I 항체, 토끼 단클론항체

데이터시트리뷰관련제품프로토콜
Human ST6GAL1 항체 제품 정보
면역원:Recombinant Human ST6GAL1 / ST6GAL-I protein (Catalog#11590-H07H)
Clone ID:036
면역글로불린(Ig) 유형:Rabbit IgG
농도:
내독소:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
제조방법:This antibody was obtained from a rabbit immunized with purified, recombinant Human ST6GAL1 / ST6GAL-I (rh ST6GAL1 / ST6GAL-I; Catalog#11590-H07H; P15907; Lys27-Cys406).
Human ST6GAL1 항체 사용 가이드
특이성:Human ST6GAL1 / ST6GAL-I
적용:IHC-P

IHC-P: 1-10 μg/mL

보관:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Human ST6GAL1 Antibody IHC Application Image
ST6GAL1 / CD75 Antibody, Rabbit MAb, Immunohistochemistry
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Caption:
Immunochemical staining of human ST6GAL1 in human kidney with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
ST6GAL1 / CD75 Antibody, Rabbit MAb, Immunohistochemistry
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Caption:
Immunochemical staining of human ST6GAL1 in human prostate with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to epithelium.
Other ST6GAL1 Antibody Products
ST6GAL1/ST6GAL-I 연구배경

Beta-galactoside alpha-2,6-sialyltransferase 1, also known as B-cell antigen CD75, Sialyltransferase 1, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6GAL1 and SIAT1, is a single-pass type II membrane protein which belongs to the glycosyltransferase 29 family. Sialyltransferases are key enzymes in the biosynthesis of sialoglycoconjugates that catalyze the transfer of sialic residue from its activated form to an oligosaccharidic acceptor. ST6GAL1 / SIAT1 is normally found in the?Golgi?but which can be proteolytically processed to a soluble form. It is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. β-Galactoside α2,6-sialyltransferases ST6GAL1 and ST6GAL2 are the two unique members of the ST6GAL family described in higher vertebrates. ST6GAL1 / SIAT1 transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.

Human ST6GAL1/ST6GAL-I 참고자료
  • Collins,B.E. et al., 2006, Nat Immunol. 7(2):199-206.
  • Videira,P.A. et al., 2008, Glycoconj J. 25(3): 259-68.
  • Petit,D. et al., 2010, J Biol Chem. 285(49): 38399-414.
  • Kroes,R.A. et al., 2010, Proc Natl Acad Sci USA.107(28):12646-51.
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    Size / Price
    Cat No: 11590-R036-50
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    가격:      (You Save: )
    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
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