All Transferrin Receptor reagents are produced in house and quality controlled, including 24 Transferrin Receptor Antibody, 54 Transferrin Receptor Gene, 3 Transferrin Receptor IPKit, 4 Transferrin Receptor Lysate, 4 Transferrin Receptor Protein, 3 Transferrin Receptor qPCR. All Transferrin Receptor reagents are ready to use.
Recombinant Transferrin Receptor proteins are expressed by HEK293 Cells with fusion tags as N-His, N-human IgG1-Fc.
Transferrin Receptorantibodies are validated with different applications, which are FCM, WB, ELISA, IP, ICC/IF, IF, IHC-P.
Transferrin ReceptorcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Transferrin Receptor of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Expression host: HEK293 Cells
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p90, CD71 and TFRC, is a single-pass type II membrane protein which belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target.