UCHL3 항체, 토끼 다클론 항체, Antigen Affinity Purified

  • UCHL3 Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot
  • UCHL3 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunoprecipitation
데이터시트리뷰관련제품프로토콜
 UCHL3 항체 제품 정보
면역원:Recombinant Rat UCHL3 protein (Catalog#80087-R07E)
Clone ID:
면역글로불린(Ig) 유형:Rabbit IgG
농도:
내독소:
Formulation:0.2 μm filtered solution in PBS
제조방법:Produced in rabbits immunized with purified, recombinant Rat UCHL3 (rR UCHL3; Catalog#80087-R07E; Q91Y78; Glu 2-Ala 230). UCHL3 specific IgG was purified by Rat UCHL3 affinity chromatography.
 UCHL3 Antibody WB Application Image
 UCHL3 Antibody IP Application Image
Other UCHL3 Antibody Products
UCHL3 연구배경

Ubiquitin carboxyl-terminal hydrolase isozyme L3, also known as UCH-L3, Ubiquitin thioesterase L3 and UCHL3, is a ubiquitin-protein hydrolase which belongs to the peptidase C12 family. It is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. UCHL3 is highly expressed in heart, skeletal muscle, and testis. UCHL1 and UCHL3 are two of the deubiquitinating enzymes expressed in the brain. These phenotypes indicate the importance of UCHL1 and UCHL3 in the regulation of the central nervous system. UCHL3 functions as a de-ubiquitinating enzyme where lack of its hydrolase activity may result in the prominent accumulation of ubiquitinated proteins and subsequent induction of stress responses in skeletal muscle. UCHL3 has also been identified as a tumor-specific antigen in colon cancer.

 UCHL3 참고자료
  • Wood,M.A. et al., 2005, Hippocampus  15 (5):610-21.
  • Kwon,J. et al., 2006, Exp Anim  55 (1):35-43.
  • Setsuie,R. et al., 2009, Neurochem Int  54 (5-6):314-21.
  • Setsuie,R. et al., 2010, Neurochem Int  56 (8):911-8.
  • Product nameProduct name
    Size / Price
    Cat No: 80087-RP02-50
    정가: 
    가격:      (You Save: )

    Datasheet & Documentation

    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".