Anti-VEGF165 Antibody

Cat: 11066-R105

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Anti-VEGF165 Antibody (Rabbit Monoclonal antibody) General Information

Product name
Anti-VEGF165 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human VEGFA
Has cross-reactivity in ELISA with
Mouse VEGF164
Human VEGF121
No cross-reactivity in ELISA with
Human VEGFC
Immunogen
Recombinant Human VEGF / VEGFA / VEGF165 protein (Catalog#11066-HNAB)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human VEGF / VEGFA / VEGF165 (rh VEGF / VEGFA / VEGF165; Catalog#11066-HNAB; P15692-4; Met 1-Arg 191).
Source
Monoclonal Rabbit IgG Clone #105
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Anti-VEGF165 Antibody (Rabbit Monoclonal antibody) Validated Applications

Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-VEGF165 Antibody Alternative Names

Anti-MVCD1 Antibody;Anti-VEGF Antibody;Anti-VEGF165 Antibody;Anti-VPF Antibody

VEGFA Background Information

Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
vascular endothelial growth factor A
References
  • Woolard J. et al. (2004) VEGF165b, an inhibitory vascular endothelial growth factor splice variant: mechanism of action, in vivo effect on angiogenesis and endogenous protein expression. Cancer Res. 64(21): 7822-7835.
  • Jia SF, et al. (2008) VEGF165 is necessary to the metastatic potential of Fas(-) osteosarcoma cells but will not rescue the Fas(+) cells. J Exp Ther Oncol. 7(2): 89-97.
  • Cimpean AM, et al. (2008) Vascular endothelial growth factor A (VEGF A) as individual prognostic factor in invasive breast carcinoma. Rom J Morphol Embryol. 49(3): 303-8.
  • Hamdollah Zadeh MA, et al. (2008) VEGF-mediated elevated intracellular calcium and angiogenesis in human microvascular endothelial cells in vitro are inhibited by dominant negative TRPC6. Microcirculation. 15(7): 605-14.
  • Eisenach PA, et al. (2010) MT1-MMP regulates VEGF-A expression through a complex with VEGFR-2 and Src. J Cell Sci. 123(Pt 23):4182-4193.
  • Claesson-Welsh L (2010) Gremlin: vexing VEGF receptor agonist. Blood. 116(18):3386-7.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-VEGF164 Antibody Rabbit Monoclonal ELISA 80006-R003
    Anti-VEGF164 Antibody Rabbit Polyclonal ELISA 80006-RP01
    Anti-VEGF164 Antibody Rabbit Monoclonal ELISA(Cap) 80006-R001
    Anti-VEGF164 Antibody Rabbit Polyclonal ELISA 80006-T16
    Anti-VEGF164 Antibody Rabbit Polyclonal ELISA 50159-RP01
    Anti-VEGF164 Antibody Rabbit Polyclonal ELISA 50159-T16
    Anti-VEGF165 Antibody Mouse Monoclonal ELISA,ELISA(Det) 11066-MM04
    Anti-VEGFA Antibody Mouse Monoclonal IHC-P 101465-MM12
    Anti-VEGF121 Antibody Rabbit Polyclonal WB,ELISA 10008-RP01
    Anti-VEGFA Antibody Mouse Monoclonal IHC-P 101465-MM02
    Anti-VEGFA Antibody Rabbit Polyclonal WB,IP 100253-T36
    Anti-VEGF183 Antibody Rabbit Polyclonal ELISA,IHC-P 10009-RP02
    Anti-VEGF121 Antibody Rabbit Polyclonal WB,ELISA 10008-RP02
    Anti-VEGF121 Antibody Rabbit Monoclonal ELISA(Cap) 10008-R145
    Anti-VEGF165 Antibody Rabbit Polyclonal ELISA 11066-T16
    VEGF / VEGFA / VEGF165 Neutralizing Antibody Rabbit Monoclonal Neutralization 11066-R010
    Anti-VEGF121 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 10008-R064
    Anti-VEGF183 Antibody Rabbit Polyclonal ELISA 10009-RP01
    Anti-VEGF121 Antibody Rabbit Polyclonal ELISA,IHC-P,ICC/IF,IF 10008-T26
    Anti-VEGF121 Antibody Rabbit Polyclonal ELISA,IHC-P 10008-T24
    Anti-VEGF165 Antibody Rabbit Polyclonal ELISA,ICC/IF,IF 11066-T18
    VEGF / VEGFA / VEGF165 Neutralizing Antibody Rabbit Monoclonal Neutralization 11066-R012
    Anti-VEGFA Antibody Mouse Monoclonal IHC-P 101465-MM13
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