Anti-IL1-F8 Antibody


Anti-IL1-F8 Antibody (Rabbit Monoclonal antibody) General Information

Product name
Anti-IL1-F8 Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse IL1-F8
Recombinant Mouse IL36B/IL1F8 Protein (Catalog#51071-MNAE)
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL36B/IL1F8 (rM IL36B/IL1F8; Catalog#51071-MNAE; Q9D6Z6; Met1-Lys183).
Monoclonal Rabbit IgG Clone #110
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-IL1-F8 Antibody (Rabbit Monoclonal antibody) Validated Applications

Application Dilution
WB 1:500-1:2000
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-IL1-F8 Antibody (Rabbit Monoclonal antibody) Images

Anti-IL1F8 rabbit monoclonal antibody at 1:500 dilution

Lane A: Mouse liver tissue lysate

Lane B: Mouse kidney tissue lysate

Lysates/proteins at 30 μg per lane.


Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

Developed using the ECL technique.

Performed under reducing conditions.

Predicted band size:21 kDa

Observed band size:25 kDa

Anti-IL1-F8 Antibody: Alternative Names

Anti-2310043N20Rik Antibody; Anti-Il36b Antibody; Anti-RP23-176J12.1 Antibody

IL1-F8 Background Information

Interleukin-1 family member 8(IL1F8) also known as IL36B, is a member of the interleukin 1(IL-1) cytokine family. IL1F8 may contains a 12-stranded beta-trefoil structure. Until recently, the IL-1 family of cytokines includ four members, with three having pro-inflammatory effects such as IL1F8 and the fourth member being an IL-1 receptor antagonist (IL-1Ra). IL-1 family members exert their effects through binding to receptors that belong to the IL-1 receptor (IL-1R) family. IL1F8 exerts proinflammatory effects in primary human joint cells. Joint and serum IL-1F8 protein levels did not correlate with inflammation, but they were high in some human serum samples tested, including samples from patients with rheumatoid arthritis. IL1F8 also activated NK-κB.
Full Name
interleukin 36, beta
  • Magne D, et al. (2006) The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes. Arthritis Research & Therapy. 8: R80.
  • Smith DE, et al. (2000) The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes. The Journal of Biological Chemistry. 275: 1169-75.
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