|Send Mab Seq||Receive Purified Mab||Make Payment Upon Satisfaction||Inquire Now!
|No Upfront Payment!||No Risk to You!||You Order,We Deliver!|
Sino Biological's has developed transient transfection technology in HEK293 cells for antibody Fab expression and production, and has generated excellent quality of Fab fragment for antigen-Fab co-crystallization. The recombinant antibody Fab fragment protein produced by our transient transfection in mammalian cells is of superior quality than antibody fragment protein generated from enzyme cleavage of full antibodies. If customers prefer, we can also use our E. coli. expression system for antibody Fab production.
Because many antibody Fab fragment proteins do not bind well to protein A, protein G, or protein L affinity resin, we typically add a poly-histidine tag at the C-terminus of the antibody heave chain for purification. A protease cleavage site can be designed between the His-tag and the Fab to allow tag-removal after purification if needed.
You Pay on Deliverable, Risk-Free:
For customers that have set up a contract service account with us, we typically do not require an upfront payment for antibody production orders. For antibody production request, we usually quote our price based on successful completion of the production project, and you only need to pay upon receiving the purified antibodies and invoice. However, for some risky antibody production projects, for example, production of antibodies with modified constant regions, we would need to charge a small amount of cost for feasibility pilot study and process development (if needed).
How to Submit a Request for Antibody Fab Production Service?
If you are interested in using our antibody Fab production services to support your antibody discovery and development program, please contact us by leaving an on-line message or send us your detailed request to CROfirstname.lastname@example.org. Based on the quantity and quality requirement of your request, a formal quote will be send back to you for your review, comment, and/or acceptance.