Cathepsin K cDNA ORF Clone in Cloning Vector, Human


Cathepsin K cDNA ORF Clone in Cloning Vector, Human: General Information

NCBI Ref Seq
RefSeq ORF Size
990 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Full length Clone DNA of Human cathepsin K.
Sequencing Primers
M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.

Cathepsin K cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

Cathepsin K cDNA ORF Clone in Cloning Vector, Human: Alternative Names

CTS02 cDNA ORF Clone, Human; CTSO cDNA ORF Clone, Human; CTSO1 cDNA ORF Clone, Human; CTSO2 cDNA ORF Clone, Human; PKND cDNA ORF Clone, Human; PYCD cDNA ORF Clone, Human

Cathepsin K Background Information

Pycnodysostosis is an autosomal recessive skeletal dysplasia caused by pathogenic variants in the cathepsin K ( CTSK ) gene. Cathepsin K (CTSK) is an important protease responsible for degrading type I collagen, osteopontin, and other bone matrix proteins. The mutations in the CTSK gene can cause pycnodysostosis (OMIM 2658), a rare autosomal recessive bone dysplasia. Deficiency of cathepsin K (CTSK), a lysosomal cysteine protease, has been shown earlier as a cause of an autosomal recessive osteosclerotic skeletal dysplasia pycnodysostosis.
Full Name
cathepsin K
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