Ephrin B3 / EFNB3 항체, 토끼 다클론항체

데이터시트리뷰프로토콜
발현 숙주: Human Cells  
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51147-M02H-50
51147-M02H-100
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발현 숙주: Human Cells  
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51147-M08H-50
51147-M08H-100
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발현 숙주: Human Cells  
  • Slide 1
80112-R02H-50
80112-R02H-100
50 µg 
100 µg 
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발현 숙주: Human Cells  
  • Slide 1
80112-R08H-50
80112-R08H-100
50 µg 
100 µg 
Add to Cart

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Ephrin B3 / EFNB3 antibody 연구배경

Ephrin B3 belongs to the ephrin family. Ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin B3 is important in brain development as well as in its maintenance. It is especially important for forebrain function since its expression levels were particularly high in several forebrain subregions compared to other brain subregions. Ephrin B3 binds to, and induce the collapse of, commissural axons/growth cones in vitro. It may play a role in constraining the orientation of longitudinally projecting axons.

 Ephrin B3 / EFNB3 antibody 참고자료
  • Takemoto M, et al. (2002) Ephrin-B3-EphA4 interactions regulate the growth of specific thalamocortical axon populations in vitro. Eur J Neurosci. 16(6):1168-72.
  • Brckner K, et al. (1999) EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. Neuron. 22(3):511-24.
  • Bergemann A, et al. (1998) Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube. Oncogene. 16(4):471-80.
  • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".